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Initiator Peptide Workstation
Manual Microwave Peptide Synthesis

Key Features
  • Enables microwave assisted peptide synthesis
  • Reusable 2-5 mL or 10-20 mL microwave peptide vials
  • Disposable HDPE frit
  • Reusable snap cap
  • Height adjustable vacuum head
  • Use in Initiator without system modifications
  • Microwave cleavage on the same platform
  • Compact footprint
Initiator Peptide Workstation
Wash Station shown with centrifuge tube (left)
Wash Station shown with GL 45 glass bottle (right)

Rapidly synthesize high quality peptides
using microwave irradiation

The Initiator Peptide Workstation is an accessory to perform manual microwave peptide synthesis and cleavage utilizing the Biotage Initiator microwave synthesizer.

The Initiator Peptide Workstation consists of a specially designed microwave peptide vial and wash station to enable the synthesis of peptides using the Initiator without any system modifications.

Peptide synthesis is performed in the microwave peptide vial utilizing the Initiator under atmospheric conditions. The vial contents are filtered and washed using the wash station.

This is a cost-effective way to enjoy the benefits of microwave assisted solution and solid phase peptide synthesis.


Microwave Peptide Vials
The microwave peptide vial is available in two different sizes; 2-5 mL for 75-150 µmol scale or 10-20 mL for 250-500 µmol scale (depending on resin loading). The complete vial is easily assembled and consists of a glass vial, HDPE frit, check valve and snap cap with septum.

Wash Station
The wash station consists of a specially designed height adjustable vacuum head on a stand. When connected to a vacuum pump, this allows the microwave peptide vial to be easily emptied when positioned on the vacuum head. Material can be collected in a standard GL 45 laboratory glass bottle, 50 mL centrifuge tube or even a round bottom flask.

Economically Synthesize Difficult Sequences
Use microwave irradiation and standard reagents to synthesize difficult sequences that are problematic or even impossible to synthesize using standard methods.

Faster Synthesis
Reduce cycle times by using microwave irradiation and fast manual washing and emptying.

Versatile
Allows solution and solid phase peptide synthesis, cleavage of peptides and post-synthetic modification of peptides using microwave irradiation.

The Workstation can also be used to perform other types of chemistry, e.g. organic, PNA and peptoid synthesis.

Reduce Costs
When using expensive reagents you can manually add the exact amount of reagent while minimizing waste and costs.


Specifications

Two microwave peptide vial sizes available:
2-5 mL for 75-150 µmol scale or 10-20 mL for 250-500 µmol scale (depending on resin loading)
Agitation:  Variable magnetic stirrer (recommend 300-600 rpm)
Initiator type:  with EXP function only (disconnect robot and restart system)
Wash station vacuum seal
viton seal as standard, kalrez seal available as an option
Wash station vacuum head fits
standard GL 45 (45 mm diameter neck size) laboratory glass bottles, 50 mL centrifuge tube and round bottom flasks (B24 and larger)
Dimensions:  180 x 190 x 340 mm (W x D x H)
Weight:  1.5 kg

 

Ordering Information

Part # Description
355985 Initiator Peptide Workstation, 2-5 mL vial (355964 + 355968)
355986 Initiator Peptide Workstation, 10-20 mL vial (355965 + 355968)
355964 2-5 mL microwave peptide vial kit including additional septum (5), frit (5), and check valve o-ring (2)
355965 10-20 mL microwave peptide vial kit including additional septum (5), frit (5), and check valve o-ring (2)
355968 Wash Station, qty 1
355814 1000mL GL 45 laboratory glass bottle, qty 1
355782 2-5 mL microwave peptide vial glass barrel, qty 1
355803 10-20 mL microwave peptide vial glass barrel, qty 1
355957 Check valve, qty 1
355962 Check valve o-ring, kalrez, qty 2
355804 Snap cap, qty 1
355960 Septum, qty 5
355961 HDPE frit, qty 5
355984 Magnetic stirring bar for 2-5mL vials, qty 5
353930 Magnetic stirring bar for 10-20mL vials, qty 5
355959 Vacuum seal, kalrez, qty 1
355966 Vacuum seal, viton, qty 5
355967 Rubber foot, wash station, qty 4
   
Peptide Synthesis and Purification Brochure
Peptide Synthesis Brochure
Related Information

Initiator

Biotage® Initiator

The Biotage Initiator microwave synthesizer enables chemists to quickly synthesize compounds using microwave heating. In addition to speed, microwave synthesis offers other advantages such as simplicity and broader exploration.

Through superior heating features, the Biotage Initiator is able to quickly achieve temperatures and pressures beyond the traditional reflux heating. This allows chemists to perform complex reactions formerly not possible and is, therefore, the fastest growing technology in the pharmaceutical research laboratory.

Chemists can now safely access the benefits of microwave assisted peptide synthesis using the Biotage Initiator and the Initiator Peptide Workstation.

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