« Return to Microwave Synthesis Home Page
Biotage® Initiator+
Microwave Synthesizer
|
Features and Advantages
- 300 °C reaction temperature
- 30 bar reaction pressure
- In situ temperature measurement
- Upgradable to run peptide synthesis
- Large 10" touchscreen
- Modular automation solutions
- Guided step-by-step wizard
- Safe and simple
|
 |
Rapid, microwave-assisted organic synthesis for
processing and method development
The Biotage Initiator+ represents a new generation of instruments for organic, medicinal, materials, nano and polymer chemistry professionals. It is an upgradeable and reliable platform for chemists to make great discoveries.
 |
The Biotage Initiator+ is a flexible system that utilizes all Biotage vials, from 0.2 to 20 mL, in any order or combination, at any time without system modifications, delivering greater flexibility and direct scale-up from milligrams to grams.
Biotage Initiator+ can also be upgraded with automation solutions to achieve higher throughput to save time and cost. |
Flexibility
Higher temperatures and pressures of up to 300 °C and 30 bar open new possibilities to perform difficult reactions. This allows for more flexibility in choosing a solvent. Even low boiling point solvents can now be run at higher temperatures. Using “Regulate on pressure” enables the reaction to reach highest possible temperature during the run. With the addition of the optional fiber optic probe, it is possible to measure the reaction temperature inside the vial for a higher degree of control.
Upgradable
Upgrade from an Biotage Initiator+ by connecting the SP Wave peptide synthesis module and the Robot Eight kit to perform microwave assisted peptide synthesis with vortex mixing to ensure homogeneous heat distribution.
Easy to operate
The large touch screen display provides an easy-to-use experience from set-up to results. By using the Biotage Wizard, the user is guided through the set-up of experiments step-by-step. It also includes assistance in converting conventional conditions to microwave synthesis parameters.
Modular
The modular design allows a user to add on different automated sample processors dependent on throughput requirements.
Safe
The reaction vessel is secured with a triple-tier safety lock to ensure maximum operator safety at all times. This in combination with high grade aluminum and a safe explosion box ensures maximum operator safety, even at high temperature and pressure.
Specifications
| Heating Process |
|
| Temperature range |
40–300°C1 |
| Temperature increase |
Typically 2-5 °C/sec depending on solvent and power applied |
| Reaction time |
Up to 96 hours. |
| |
Typically, most reactions require 2 to 15 minutes of irradiation. |
| Pressure range |
0–302 bar (3 MPa; 435 psi) |
| Power range |
0–400 W from magnetron at 2.45 GHz |
| Reaction volumes |
0.2–20 mL |
| Agitation |
Variable magnetic stirrer (300-900 RPM) |
| |
|
| Sample Processor |
Upgradable with Robot Eight / Robot Sixty |
| |
Processing capacity 8 vials / 60 vials |
| |
Rack capacity (large) 2x2 vials / 2x12 vials |
| |
Rack capacity (small) 2x4 vials / 2x30 vials |
| |
|
| System Requirements |
|
| Temperature |
Operating Temperature: 18–32°C |
| |
Storage and transportation temperature: -25°C to 60°C |
| Humidity |
20–95% at room temperature |
| Electrical supply |
Europe: 220–240 V~, 50 Hz (5 A) |
| |
US and Japan: 100–120 V~, 50/60 Hz (10 A) |
| Maximum power consumed |
1100 VA |
| Cooling |
Pressurized air supply: > 60 l/min (2.1 cubic feet/min), 2.5 to 4.0 bar |
| |
(0.25 to 0.40 MPa; 36 to 58 psi) |
| Weight |
Initiator+: 21 kg (48.5 lbs) |
| Dimensions (WxDxH) |
Initiator+: 365 x 422 x 421 mm (14.4"x 16.6" x 16.6") |
| Max sound level |
70 dB(A) |
| |
|
| Interfaces |
|
| Touch screen |
10.4" |
| Ethernet LAN |
Complies with IEEE 802.3 (ANSI 8802-3) |
| USB |
USB 2.0 |
| Achiving/back-up |
Via USB |
| Printing |
Via LAN |
| |
|
| Upgrade Path |
The Initiator system can be upgraded to an automated 8- or 60-position system, it can also be equipped with the SP Wave module for an automation solution for peptide chemistry, complete with vortex mixer and liquid handling. |
| |
|
| Certifications |
CE, CSA certified |
1Temperature range is limited to 40–250°C for the 10-20 mL vessel
2Pressure range is limited to 0-20 bar for the 10-20 mL vessel
Ordering Information
| Part Number |
Description |
| 356006 |
Biotage Initiator+ System (EU) |
| 356007 |
Biotage Initiator+ System (USA/JPN) |
| 355380 |
Robot Eight for Initiator System |
| 355381 |
Robot Sixty for Initiator System |
| 356014 |
Biotage Initiator+ SP Wave Microwave Peptide System (EU) |
| 356015 |
Biotage Initiator+ SP Wave Microwave Peptide System (USA/JPN) |
| Optional Accessories and Consumables |
| 355458 |
Microwave Vials 0.2-0.5 mL, qty 100 |
| 352016 |
Microwave Vials 0.5-2 mL, qty 100 |
| 351521 |
Microwave Vials 2-5 mL, qty 100 |
| 354833 |
Microwave Vials 10-20 mL, qty 50 |
| |
|