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Biotage and Peptide SynthesisComing soon: Isolera™ Dalton - Flash Chromatography with Integrated Mass IdentificationISOLUTE® Myco SPE columns, a dedicated product for the efficient extraction of mycotoxins from food matricesTLC-to-Step Gradient capability significantly reduces both purification time and solvent useBiotage Releases New Catalog and Technical Guide for Sample Preparation and EvaporationBiotage moving into Mass Directed Flash
 

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Biotage® Isolera Prime 
Flash Purification System

Isolera Prime

Value-priced, advanced flash purification

Biotage Isolera Prime is the new standard in value-priced flash purification systems delivering a full range of features and cost-saving benefits. This flexible system is upgradeable and grows with the needs of laboratories and universities where value is especially important. Isolera Prime is compatible with Biotage flash cartridges, including the new value-priced Biotage ZIP™.

Biotage Isolera Prime is the newest addition to the acclaimed Isolera automated flash system family, specifically designed for chemists needing an automated purification platform to increase productivity delivering high value and just the right features.

Features and Advantages

  • Value based system with a full range of features
  • Solvent-saving Gradient Optimization can reduce solvent use up to 60% lowering system
  • Upgradeable and grows to your needs
  • 145 psi (10 bar) pressure capability enables both normal-phase and reversed-phase purification
  • Patented TLC-to-Gradient feature eliminates method development guessing and re-runs
  • Up to 100 mL/min flow rate to speed purification
  • Utilizes new Biotage ZIP cartridges and high performance Biotage SNAP cartridges
  • Small footprint minimizes bench and hood space
  • Large 10.4 inch (26.4 cm) touchscreen with large buttons simplifies user interaction
  • Easy to use software enables fast method development
  • Two UV detector options to address different application needs
  • Utilizes 2 solvents simultaneously providing binary gradient
  • 4.8-L fraction capacity minimizes rack changes
TLC to Gradient Touch screen
TLC-to-gradient feature delivers optimal purification Large, easy-to-read and use touch screen


Value
The Biotage Isolera Prime delivers more than just the basics. Also included are a patented TLC-to-Gradient feature that eliminates method development guesswork and a solvent-saving gradient optimization function that reduces solvent use by up to 60%. Cost savings are further realized with use of the new value-priced, high performing Biotage ZIP cartridges available in wide range of sizes.

Performance
Biotage Isolera Prime performs at flow rates up to 100 mL/min with a  pressure range up to 145 psi (10 bars). The built-in detector (fixed 254 nm or variable wavelengths 200–400 nm) provides excellent detection for aromatic and conjugated organic compounds and can trigger fractionation using threshold, slope, or volume parameters.

Flexibility
The Biotage Isolera Prime can be upgraded and customized to any laboratory’s requirements with the addition of a range of accessories, including external dry-loading vessels, leak detector, fraction racks and cartridge holders. Biotage also offers the widest range of flash cartridges for higher performance and scalability including the new value priced Biotage ZIP, industry-standard Biotage SNAP, FLASH+® and ISOLUTE® products available in sizes from 5–750 g.

Specifications 

Solvent delivery Constant volume electric HPFC pump
Flow rate 5–100 mL/min.
Pressure limit 145 psi (10 bar)
UV Detection Choice of variable dual-wavelength (200–400 nm) or fixed (254 nm) detector
Flow cell path length 0.3 mm
UV collection modes Single wavelength, Dual wavelength (variable UV)
Fractionation modes Volume, threshold, threshold with volume, low slope, medium slope, custom slope
Collection vessels Test tubes (13, 16, 18, and 25 mm) and bottles (120, 240, and 480 mL)
Power 100–240 VAC, 50/60 Hz, 4.0 A
System control and
data management
On-board computer with 10.4” diagonal touch screen interface
Dimensions
(W x H x D)
355 mm x 596 mm  x 497 mm
(14 in. x 23.5 in. x 9.6 in.)
Weight 30 kg (66 lbs.)
Certifications CE, cTÜVus

 

Ordering Information

Part Number
Description
ISO-PSF
Biotage Isolera Prime with fixed wavelength detector and 4.8 L fraction capacity
ISO-PSV Biotage Isolera Prime with variable wavelength detector and 4.8 L fraction capacity
Accessories
411789 13 x 100 mm test tube rack, 4/pk
411790 16 x 100 mm test tube rack, 4/pk
411791 16 x 150 mm test tube rack, 4/pk
411792 18 x 150 mm test tube rack, 4/pk
411793 25 x 150 mm test tube rack, 4/pk
411794 120 mL bottle rack, 4/pk
411934 240 mL bottle rack, 1/pk
411929 480 mL bottle rack, 1/pk
413092 Biotage ZIP 5 g/10 g cartridge holder
413302 Biotage ZIP 30 g cartridge holder
413303 Biotage ZIP 45 g cartridge holder
413304 Biotage ZIP 80 g cartridge holder
413305 Biotage ZIP 120 g cartridge holder
411922 Biotage SNAP 10 g cartridge holder
411776 Biotage SNAP 25 g cartridge holder
411923 Biotage SNAP 150 g/ 100 g cartridge holder
411924 Biotage SNAP 340 g cartridge holder
412422 Biotage SNAP 750 g/ 1500 g cartridge holder
412019 Leak detector, single fraction collection bed
   
Flash Purification Systems Brochure
Flash Purification Systems Brochure
Related Information
Accessories
» Biotage Isolera™ ELSD-1080
Consumables
» Biotage ZIP® Sphere
» Biotage ZIP™ Cartridges
» Biotage SNAP Cartridges
» Biotage SNAP Ultra Cartridges
» ISOLUTE® Cartridges
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