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Biotage® Isolera Prime ™ Flash Purification System

Value-priced, advanced flash purification
Biotage Isolera Prime is the new standard in value-priced flash purification systems delivering a full range of features and cost-saving benefits. This flexible system is upgradeable and grows with the needs of laboratories and universities where value is especially important. Isolera Prime is compatible with Biotage flash cartridges, including the new value-priced Biotage ZIP™.
Biotage Isolera Prime is the newest addition to the acclaimed Isolera automated flash system family, specifically designed for chemists needing an automated purification platform to increase productivity delivering high value and just the right features.
Features and Advantages
- Value based system with a full range of features
- Solvent-saving Gradient Optimization can reduce solvent use up to 60% lowering system
- Upgradeable and grows to your needs
- 145 psi (10 bar) pressure capability enables both normal-phase and reversed-phase purification
- Patented TLC-to-Gradient feature eliminates method development guessing and re-runs
- Up to 100 mL/min flow rate to speed purification
- Utilizes new Biotage ZIP cartridges and high performance Biotage SNAP cartridges
- Small footprint minimizes bench and hood space
- Large 10.4 inch (26.4 cm) touchscreen with large buttons simplifies user interaction
- Easy to use software enables fast method development
- Two UV detector options to address different application needs
- Utilizes 2 solvents simultaneously providing binary gradient
- 4.8-L fraction capacity minimizes rack changes
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| TLC-to-gradient feature delivers optimal purification |
Large, easy-to-read and use touch screen |
Value The Biotage Isolera Prime delivers more than just the basics. Also included are a patented TLC-to-Gradient feature that eliminates method development guesswork and a solvent-saving gradient optimization function that reduces solvent use by up to 60%. Cost savings are further realized with use of the new value-priced, high performing Biotage ZIP cartridges available in wide range of sizes.
Performance Biotage Isolera Prime performs at flow rates up to 100 mL/min with a pressure range up to 145 psi (10 bars). The built-in detector (fixed 254 nm or variable wavelengths 200–400 nm) provides excellent detection for aromatic and conjugated organic compounds and can trigger fractionation using threshold, slope, or volume parameters.
Flexibility The Biotage Isolera Prime can be upgraded and customized to any laboratory’s requirements with the addition of a range of accessories, including external dry-loading vessels, leak detector, fraction racks and cartridge holders. Biotage also offers the widest range of flash cartridges for higher performance and scalability including the new value priced Biotage ZIP, industry-standard Biotage SNAP, FLASH+® and ISOLUTE® products available in sizes from 5–750 g.
Specifications
| Solvent delivery |
Constant volume electric HPFC pump |
| Flow rate |
5–100 mL/min. |
| Pressure limit |
145 psi (10 bar) |
| UV Detection |
Choice of variable dual-wavelength (200–400 nm) or fixed (254 nm) detector |
| Flow cell path length |
0.3 mm |
| UV collection modes |
Single wavelength, Dual wavelength (variable UV) |
| Fractionation modes |
Volume, threshold, threshold with volume, low slope, medium slope, custom slope |
| Collection vessels |
Test tubes (13, 16, 18, and 25 mm) and bottles (120, 240, and 480 mL) |
| Power |
100–240 VAC, 50/60 Hz, 4.0 A
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System control and data management |
On-board computer with 10.4” diagonal touch screen interface
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Dimensions (W x H x D) |
355 mm x 596 mm x 497 mm (14 in. x 23.5 in. x 9.6 in.) |
| Weight |
30 kg (66 lbs.) |
| Certifications |
CE, cTÜVus |
Ordering Information
Part Number
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Description
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ISO-PSF
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Biotage Isolera Prime with fixed wavelength detector and 4.8 L fraction capacity |
| ISO-PSV |
Biotage Isolera Prime with variable wavelength detector and 4.8 L fraction capacity |
| Accessories |
| 411789 |
13 x 100 mm test tube rack, 4/pk |
| 411790 |
16 x 100 mm test tube rack, 4/pk |
| 411791 |
16 x 150 mm test tube rack, 4/pk |
| 411792 |
18 x 150 mm test tube rack, 4/pk |
| 411793 |
25 x 150 mm test tube rack, 4/pk |
| 411794 |
120 mL bottle rack, 4/pk |
| 411934 |
240 mL bottle rack, 1/pk |
| 411929 |
480 mL bottle rack, 1/pk |
| 413092 |
Biotage ZIP 5 g/10 g cartridge holder |
| 413302 |
Biotage ZIP 30 g cartridge holder |
| 413303 |
Biotage ZIP 45 g cartridge holder |
| 413304 |
Biotage ZIP 80 g cartridge holder |
| 413305 |
Biotage ZIP 120 g cartridge holder |
| 411922 |
Biotage SNAP 10 g cartridge holder |
| 411776 |
Biotage SNAP 25 g cartridge holder |
| 411923 |
Biotage SNAP 150 g/ 100 g cartridge holder |
| 411924 |
Biotage SNAP 340 g cartridge holder |
| 412422 |
Biotage SNAP 750 g/ 1500 g cartridge holder |
| 412019 |
Leak detector, single fraction collection bed |
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