Biotage,IST, Argonaut, ISOLUTE, SPE, solid phase extraction, Analytical Chemistry, ISOLUTE, Non polar, acidic, basic, nuetral drugs, biological fluids

Non-polar SPE Columns

Column	Description	Base Silica	Applications	Material Safety Data Sheet
C18	Non-polar sorbent, manufactured using a trifunctional silane. In order to provide additional polar interactions associated with surface silanol groups, this sorbent is not endcapped.	Irregular particles with average size of 50um, and nominal 60 A porosity.	Matrix – aqueous Analytes – wide range polarity Retention mechanism – non-polar [polar, cation exchange]	ISOLUTE C18
C18(EC)	Non-polar sorbent, manufactured using a trifunctional silane and endcapped to reduce the polar secondary interactions associated with surface silanol groups.	Irregular particles with average size of 50 um and nominal 60 A porosity.	Matrix – aqueous Analytes – wide range polarity Retention mechanism – non-polar	ISOLUTE C18(EC)
MF C18	Non-polar sorbent, manufacturered using a monofunctional silcane. In order to provide additional polar interactions associated with surface silanol groups, this sorbent is not endcapped.	Irregular particle with average size of 50 um and nominal 125 A porosity.	Matrix – aqueous Analytes – wide range of polarity Retention mechanism – non-polar, [polar, cation exchange]	ISOLUTE MFC18
C8	Non-polar sorbent, manufactured using a trifunctional silcane. In order to provide additional polar interactions associated with surface silanol groups, this sorbent is not endcapped.	Irregular particles with average size of 50 um and nominal 60 A porosity.	Matrix –aqueous Analytes – wide range polarity Retention mechanism – non-polar [polar, cation exchange]	ISOLUTE C8
C8(EC)	Non-polar sorbent, manufactured using a trifunctional silcane and endcapped in order to reduce the polar secondary interactions associated with surface silanol groups.	Irregular particles with average size of 50 um and nominal 60 A porosity.	Matrix –aqueous Analytes – wide range polarity Retention mechanism – non-polar	ISOLUTE C8(EC)
C6	Non-polar sorbent, manufactured using a trifunctional silane. In order to provide additional polar interactions associated with surface silanol groups, this sorbent is not endcapped.	Irregular particles with average size of 50 um and nominal 60 A porosity.	Matrix –aqueous Analytes – wide range polarity Retention mechanism – non-polar [polar, cation exchange]	ISOLUTE C6
C4	Non-polar sorbent, manufactured using a trifunctional silane. In order to provide additional polar interactions associated with surface silanol groups, this sorbent is not endcapped.	Irregular particles with average size of 50 um and nominal 60 A porosity.	Matrix –aqueous Analytes – wide range polarity Retention mechanism – non-polar [polar, cation exchange]	ISOLUTE C4
C2	Non-polar sorbent, manufactured using a trifunctional silane. In order to provide additional polar interactions associated with surface silanol groups, this sorbent is not endcapped.	Irregular particles with average size of 50 um and nominal 60 A porosity.	Matrix –aqueous Analytes – wide range polarity Retention mechanism – non-polar [polar, cation exchange]	ISOLUTE C2
C2(EC)	Non-polar sorbent, manufactured using a trifunctional silane. This sorbent is endcapped in order to reduce polar secondary interactions associated with surface silanol groups.	Irregular particles with average size of 50 um and nominal 60 A porosity.	Matrix –aqueous Analytes – wide range polarity Retention mechanism – non-polar	ISOLUTE C2(EC)
CH(EC)	Non-polar sorbent, manufactured using a trifunctional silane.	Irregular particles with average size of 50 um and nominal 60 A porosity.	Matrix –aqueous Analytes – wide range polarity Retention mechanism – non-polar	ISOLUTE CH(EC)
PH(EC)	Non-polar sorbent, manufactured using a trifunctional silane.	Irregular particles with average size of 50 um and nominal 60 A porosity.	Matrix –aqueous Analytes – wide range polarity Retention mechanism – non-polar	ISOLUTE PH(EC)
CN	Polar sorbent that can exhibit both polar and non-polar interactions. It is manufactured using a trifunctional silane. In order to provide additional polar interactions associated with surface silanol groups, this sorbent is not endcapped.	Irregular particles with average size of 50 um and nominal 60 A porosity.	Matrix –aqueous Analytes – wide range polarity Retention mechanism – non-polar [polar, cation exchange]	ISOLUTE CN
CN(EC)	Polar sorbent that can exhibit both polar and non-polar interactions. It is manufactured using a trifunctional silane. In order to provide additional polar interactions associated with surface silanol groups.	Irregular particles with average size of 50 um and nominal 60 A porosity.	Matrix –aqueous Analytes – wide range polarity Retention mechanism – non-polar [polar, cation exchange]	ISOLUTE CN(EC)