Chemspeed SWAVE
Unattended Microwave Synthesizer

You want to fully automate your synthesis workflow with unmatched flexibility and maximum safety, using a state-of-the-art Biotage microwave synthesizer?

...SWAVE: All the benefits of microwave technology together with Chemspeed‘s unique selection of automatically exchangeable tools.

Fully automated reaction preparation
•  Addition of reagents under inert atmosphere for handling of sensitive chemicals
•  Overhead solid weighing and dispensingdirectly into the reactor for addition of:
             • Resins
             • Catalysts
             • Solid reagents
•  Automated liquid handling (unlimited number of reagents)

Automated capping and crimping
•  Space saving: no capping station required on the working tray.
•  Gripping function: transfer of the microwave vials to and from the microwave cavity.

Microwave-assisted synthesis: fast and safe
•  Single-mode microwave cavity
•  Reproducible heating
•  Optimal safety

Multi-step synthesis capabilities
Access to the crimped vial directly in the microwave cavity
for automated reagent addition

Work-up steps
•  Automated solid phase extraction on standard SPE
cartridges
•  Automated filtration
•  Available work-up techniques provided by the Accelerator
technology (liquid-liquid extraction, evaporation...)

Software
Flexible microwave software task: adjustable
power settings, multi-step heating profiles

Technical data
Microwave synthesizer
• Temperature: 60-250 °C
• Pressure: 0-20 bar
• Power: 0-300 W at 2.45 GHz
• Multi-step heating profiles
• Reaction vials:
Reaction volume 0.2 –2 0 mL, 4 sizes:
0.2-0.5, 0.5-2/ 2-5 and 10-20 mL
• Agitation: magnetic stirrer

Robotic platform
• X, Y and Z arm with rotating alpha-axis
and automatic tool exchange
• Rack capacity: 8 racks of up to30
samples (max 240 samples)
• Controlled atmosphere (inert gas)
• Dimensions (w x d x h): 1640 x 880 x
1110 mm (64.6 x 34.6 x 43.7 in.)

Liquid handling
• 4-needle pipetting head with variable
spacing from 9mm to 54mm
 • 4 high resolution syringe pumps with
10mL syringes (optional 1 mL and 25
mL) and 2 way-6 port ceramic valves
 • Septum-piercing needles

Capping and crimping tool
Single tool for capping, crimping and gripping of the microwave vials.

Optional functionalities
• Overhead solid weighing and
dispensing
-Weighing range: 1mg up to 10g
-Resolution: 0.1 mg
-Solid container capacity: 15 mL
• HPLC injection valve (up to 4 valves
possible)
• Online SPE purification

Available through ChemSpeed