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V-10  Evaporator
High Performance Concentration System for Optimized Results

Quickly and safely dry dissolved compounds

The Biotage V-10 solvent evaporation system rapidly dries samples dissolved in both aqueous and organic solvents up to 20x faster than traditional rotary or centrifugal evaporators, leaving solvent-free product in the vial. This innovative vortex and vacuum evaporation technology was developed through collaboration with major pharmaceutical companies. The high performance vacuum capability of the V-10 allows low temperature evaporation of high boiling solvents. Optimized evaporation methods protect the sample against bumping and overheating. Versatility and scalability eliminate handling and reformatting issues.

Rapid three-way drying
Evaporate samples up to 20x faster than traditional rotary or centrifugal evaporators using a patented combination of drying techniques, including high-speed vial rotation, uniform IR controlled heating, and vacuum drying. This unique system provides rapid evaporation of solvents with boiling points from 30 to 205 °C. Samples dried on a V-10 have little or no solvent residue to interfere with downstream analysis such as NMR.

Evaporation of high boiling solvents
The V-10’s high performance vacuum capability allows low temperature evaporation of high boiling solvents. Solvents include DMF, aqueous, aqueous/organic mixtures and even DMSO and NMP with the high vacuum pump option (see table 1).

Table 1. Time to evaporate 8-mL of solvent at 40º C using Hi Boil method

Versatility and Automation
V-10’s versatility enables evaporation of single samples (up to 12 mL) or large pooled volumes using V-10 pumps (syringe or peristaltic). Adding the automated vial loading/changing carousel enables unattended evaporation of up to 16 samples. Using the V-10 Control Center software, integrate the system with a liquid handling robot. Combine multiple fractions/samples from different test tube racks and dry them into a single vial in one operation

Clean and safe evaporation
Bump-free vortex evaporation prevents sample loss while the system’s precise temperature control eliminates sample overheating. Maximize sample recovery with the V-10’s automatic, end-of-run detection.

Eliminate Reformatting
Compounds are dried directly in vial of choice. Tedious tasks such as sample transfers, handling and reformatting are minimized, increasing productivity in the lab.

Enhanced Green Chemistry
This environmentally friendly system captures up to 98% of solvent vapors.

Simple Operation
The system is operated via touchpad control or the via the Control Center software. On the base unit easy-to-use touchpad control directly provides pre-programmed and user-configurable methods for optimal drying conditions. The Control Center software provides simple simultaneous control of the V10 and the integrated liquid handler.

Compact footprint
Localized key pad operation along with built-in, solvent-resistant vacuum pump and refrigerated condenser save valuable bench space.

System Specifications

Ordering Information