Products
Catalogs
Special Promotions
News & Events
Applications
Investor Relations
Investor Relations
Technical Support
Careers

Interim report January - June 2010
Biotage AB (publ) - disclosure notice of substantial holding of shares
Biotage appoints Anders Wikström as Vice President of Operations and Anthony Rees as Chief Scientific Officer

Biotage Introduces Resolux™ Peptides Purification HPLC ColumnsNew Isolera™ UV-VIS Flash Purification System delivers widest wavelength range available to chemists (Copy)Biotage Launches New Isolera™ ELS Detector, Helps Isolate Virtually Any CompoundBiotage Introduces Highly-Selective ExploraSep 96-Well Screening Plates based on Molecularly Imprinted PolymersBiotage Introduces Highly-Selective AFFINILUTE MIP

European Peptide SymposiumBiotage are Gold Sponsors.
5th - 9th September
Copenhagen, DenmarkILMAC 201021st - 24th September
Basel, SwitzerlandAOACAugust 27-28
Orlando, FL27th Montreux Symposium on LC/MS 10th - 12th November
Montreux, SwitzerlandThe 3rd EBF Open Symposium 1st - 3rd December
Barcelona, Spain
 

V-10 1.6 Evaporator
Vortex and vacuum evaporation system

V10 with Carousel V10_Under_Hood.jpg

Quickly and safely dry dissolved compounds
The Biotage V-10™ solvent evaporation system rapidly dries samples dissolved in both aqueous and organic solvents up to 20x faster than traditional rotary or centrifugal evaporators, leaving solvent-free product in the vial. This innovative vortex and vacuum evaporation technology was developed through collaboration with major pharmaceutical companies. The high performance vacuum capability of the V-10 allows low temperature evaporation of high boiling solvents. Optimized evaporation methods protect the sample against bumping and overheating. Versatility and scalability eliminate handling and reformatting issues.

Rapid three-way drying
Evaporate samples up to 20x faster than traditional rotary or centrifugal evaporators using a patented combination of drying techniques, including high-speed vial rotation, uniform IR controlled heating, and vacuum drying. This unique system provides rapid evaporation of solvents with boiling points from 30 to 205 °C. Samples dried on a V-10 have little or no solvent residue to interfere with downstream analysis such as NMR.

Evaporation of high boiling solvents
The V-10’s high performance vacuum capability allows low temperature evaporation of high boiling solvents. Solvents include DMF, aqueous, aqueous/organic mixtures and even DMSO and NMP with the high vacuum pump option (see table 1).

Solvent
BP
(° C)    
Biotage V-10
evaporation
Centrifugal
evaporation
Blow-down
evaporation
NMP 202 18 minutes N/A N/A
DMSO 180 15 minutes 180 minutes N/A
DMF 150 4 minutes 90 minutes N/A
Pyridine 115 5.5 minutes 70 minutes N/A
Water 100 9 minutes 140 minutes 240 minutes
Methanol 65 3 minutes 70 minutes 40 minutes
Cyclohexane 81 2.5 minutes 40 minutes 20 minutes

Table 1. Time to evaporate 8-mL of solvent at 40º C using Hi Boil method 


Versatility and Automation
V-10’s versatility enables evaporation of single samples (up to 12 mL) or large pooled volumes using V-10 pumps (syringe or peristaltic). Adding the automated vial loading/changing carousel enables unattended evaporation of up to 16 samples. Using the V-10 Control Center software, integrate the system with a liquid handling robot. Combine multiple fractions/samples from different test tube racks and dry them into a single vial in one operation

Clean and safe evaporation
Bump-free vortex evaporation prevents sample loss while the system’s precise temperature control eliminates sample overheating. Maximize sample recovery with the V-10’s automatic, end-of-run detection.

Eliminate Reformatting
Compounds are dried directly in vial of choice. Tedious tasks such as sample transfers, handling and reformatting are minimized, increasing productivity in the lab.

Enhanced Green Chemistry
This environmentally friendly system captures up to 98% of solvent vapors.

Simple Operation
The system is operated via touchpad control or the via the Control Center software. On the base unit easy-to-use touchpad control directly provides pre-programmed and user-configurable methods for optimal drying conditions. The Control Center software provides simple simultaneous control of the V10 and the integrated liquid handler.

Compact footprint

Localized key pad operation along with built-in, solvent-resistant vacuum pump and refrigerated condenser save valuable bench space.

V10 Close up V10_close_up.jpg

System Specifications

 

 

Sample delivery

 

Vial size compatibility 



Liquid Handling compatibility



System Requirements
Power



Gas and Pressure limit



Dimensions (W x H x L)


Weight


Certifications


Interfaces
Network connections

5-mL syringe pump and/or peristaltic pump


4 mL (3 variants)

20 mL scintillation vial

30 mL scintillation vial

Gilson 221 (use with peristaltic pump)
Gilson 222, 215 or GX271 (use with dual pumps)


110 VAC (± 10%), 60 Hz, 15A (USA)
110 VAC (± 10%), 50/60 Hz, 15A (Japan)
230 VAC (± 10%), 50 Hz, 8A (EU/UK)


Compressed Nitrogen (optional) regulated up to a maximum of 2 bar

40 cm x 53 cm x 48 cm (16” x 21” x 18.5”)
49 cm x 53 cm x 54 cm (19.5” x 21” x 21.5”)
 
45 kg (100 lb)
50 kg (111 lb)

CE 



 Rs232 or TCP/IP Switched I/O

 

 

Print Print page