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Sale of Biotage's facility in Charlottesville, Virginia
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Interim report January-September 2009

Unique Evaporation Technology Proves to be a Breakthrough Concept and Effective Time Saver for Big Pharma Biotage Partners with John Morris Scientific for Distribution in Australia and New Zealand

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March 16th - 19th

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2nd Int Chester Food Science & Technology meeting (ICFST)Chester University, United Kingdom
March 22nd - 24th

5th National Meeting on Environmental Mass SpectrometryChester University, United Kingdom
March 24th

 

MP-TsOH

Catch & Release and Scavenging SPE Basic Compounds

MP_TsOH_Columns Graphic

 

 

 

 




 

 

 

MP-TsOH is a macroporous polystyrene resin with a chemically bonded p-toluenesulfonic acid functional group. It is used for the isolation of a wide range of aliphatic, aromatic and heterocyclic amines using both catch & release and scavenging SPE protocols. MP-TsOH is available packed into SPE columns and in bulk for flow-through or batch applications. Using the catch & release SPE approach, target compounds can be isolated from a range of reaction mixtures. MP-TsOH columns can be used in a scavenging SPE mode to remove excess basic reagents, allowing neutral or acidic compounds to pass straight through to the collection vessel.

MP-TsOH columns can be used to form free amines during catch & release SPE protocols. Amine salts of weak conjugate acids (e.g., acetate, trifluoroacetate, etc.) are exchanged TsOH onto MP- columns and then released as the free amine.

Chemical Data
Base Material: Macroporous poly (styrene-co-divinylbenzene), 50–100 µm
Functional Group: p-toluenesulfonic acid
Capacity: 2.5 mmol/g
Counter Ion: Proton

 

Ordering Information
MP-TSOH Columns

 Part Number   Description         Quantity
 800477-0010-B  MP-TsOH 100 mg/3 mL  50
 800477-0025-C  MP-TsOH 250 mg/6 mL  30
 800477-0050-C  MP-TsOH 500 mg/6 mL  30
 800477-0100-D  MP-TsOH 1 g/15 mL  20
 800477-0250-E  MP-TsOH 2.5 g/25 mL           20

MP-TsOH Tabless Columns for High Throughput

 800477-0010-BG     MP-TsOH 100 mg/3 mL, tab-less       50               
 800477-0025-CG2  MP-TsOH 100 mg/3 mL, tab-less  30
 800477-0050-CG  MP-TsOH 100 mg/3 mL, tab-less  30

1 ISOLUTE tab-less 3 mL columns are compatible with the Mettler Toledo Miniblock® System.
2 ISOLUTE tab-less 6 mL columns are compatible with the ISOLUTE Array-24 System


Polymer-bound Solution Phase Selection Table

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