Biotage, Argonaut,Separtis, Tabelle für Harze in gelöster Phase, PS-Benzaldehyde, MP-Carbonate, PS-DEAM, PS-Isocyanate, MP-Isocyanate, PS-Thiophenol, MP-TMT, PS-Triphenylphosphine, PS-Trisamine, MP-Trisamine, PS-TsCl (High-Loading), PS-TsNHNH2, MP-Borohydride, PS-Carbodiimide, MP-Carbonate, MP-Cyanoborohydride, PS-DES, PS-DIEA, PS-DMAP, PS-HOBt(HL), PS-NMM, PS-PPh3-Pd, PS-TBD, MP-Triacetoxyborohydride, PS-Triphenylphosphine, PS-TsCl, MP-TsOH, MP-TsOH(65), MP-TsOH Cartridge, MP-TsO-TEMPO, ACTU PS

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Interim report January - June 2010

Biotage AB (publ) - disclosure notice of substantial holding of shares

Biotage appoints Anders Wikström as Vice President of Operations and Anthony Rees as Chief Scientific Officer

Biotage Introduces Resolux™ Peptides Purification HPLC Columns

New Isolera™ UV-VIS Flash Purification System delivers widest wavelength range available to chemists (Copy)

Biotage Launches New Isolera™ ELS Detector, Helps Isolate Virtually Any Compound

Biotage Introduces Highly-Selective ExploraSep 96-Well Screening Plates based on Molecularly Imprinted Polymers

Biotage Introduces Highly-Selective AFFINILUTE MIP

European Peptide SymposiumBiotage are Gold Sponsors.
5th - 9th September
Copenhagen, DenmarkILMAC 201021st - 24th September
Basel, SwitzerlandAOACAugust 27-28
Orlando, FL27th Montreux Symposium on LC/MS 10th - 12th November
Montreux, SwitzerlandThe 3rd EBF Open Symposium 1st - 3rd December
Barcelona, Spain

Tabelle für Harze in gelöster Phase

Scavenger	Struktur	Applications	Part Number
PS-Benzaldehyd 1,0 – 1,6 mmol/g (zum Herunterladen anklicken)		Scavenges nucleophiles; including primary amines, hydrazines, reducing agents	3 gm - 800502 10 gm -800360 25 gm - 800361 100 gm - 800362 1000 gm - 800363 Download Material Safety Data Sheet
MP-Karbonat 2,5 – 3,5 mmol/g (zum Herunterladen anklicken)		General base. Neutralizes ammonium salts, scavenges acids, acidic phenols	3 gm - 800493 10 gm - 800267 25 gm - 800268 100 gm - 800269 1000 gm - 800314 Download Material Safety Data Sheet
PS-DEAM 1,5 – 2,2 mmol/g (zum Herunterladen anklicken)		Scavenger for titanium (IV) chloride, titanium (IV) isopropoxide, boronic acids	3 gm - 800515 10 gm - 800430 25 gm - 800431 100 gm - 800432 1000 gm - 800433 Download Material Safety Data Sheet
PS-Isocyanat 1,0 – 1,7 mmol/g (zum Herunterladen anklicken)		Scavenging nucleophiles, including amines and alkoxides	3 gm - 800495 10 gm - 800260 25 gm - 800261 100 gm - 800262 1000 gm - 800311 Download Material Safety Data Sheet
NEU und verbessert! MP-Isocyanat 1,0 – 2,0 mmol/g (zum Herunterladen anklicken)		Scavenging nucleophiles, including amines and alkoxides	3 gm - 801504 10 gm - 801409 25 gm - 801410 100 gm - 801411 1000 gm - 801412 Download Material Safety Data Sheet
PS-Thiophenol 1,0 – 1,5 mmol/g (zum Herunterladen anklicken)		Scavenging alkylating agents	3 gm - 800500 10 gm - 800273 25 gm - 800274 100 gm - 800275 1000 gm - 800310 Download Material Safety Data Sheet
NEU and verbessert! MP-TMT >0.5 mmol/g (zum Herunterladen anklicken)		Scavenging palladium from aqueous and non-aqueous solutions	3 gm - 801506 10 gm - 801469 25 gm - 801470 100 gm - 801471 1000 gm - 801472 Download Material Safety Data Sheet
PS-Triphenylphosphin 2,2 mmol/g (zum Herunterladen anklicken)		Chlorination of acids and alcohols, Wittig and Mitsunobu reactions, scavenging of alkyl halides	3 gm - 800510 10 gm - 800378 25 gm - 800379 100 gm - 800380 1000 gm - 800381 Download Material Safety Data Sheet
PS-Trisamin 3,0 – 5,0 mmol/g (zum Herunterladen anklicken)		Scavenging acid chlorides, sulfonyl chlorides, isocyanates and other electrophiles	3 gm - 800501 10 gm - 800228 25 gm - 800229 100 gm - 800230 1000 gm - 800309 Download Material Safety Data Sheet
NEU and verbessert! MP-Trisamin 2,0 – 3,0 mmol/g (zum Herunterladen anklicken)		Scavenging acid chlorides, sulfonyl chlorides, isocyanates, and other electrophiles	3 gm - 801505 10 gm - 801397 25 gm - 801398 100 gm - 801399 1000 gm - 801400 Download Material Safety Data Sheet
PS-TsCl (hoch beladbar) 2,0 – 3,0 mmol/g (zum Herunterladen anklicken)		Scavenging of alcohols, amines and other nucelophiles	3 gm - 800503 10 gm - 800364 25 gm - 800365 100 gm - 800366 1000 gm - 800367
PS-TsNHNH2 1,8 – 3,2 mmol/g (zum Herunterladen anklicken)		Scavenging aldehydes and ketones	3 gm - 800497 10 gm - 800270 25 gm - 800271 100 gm - 800272 1000 gm - 800317 Download Material Safety Data Sheet
Polymer-gebundene Reagenzien	Struktur	Applications	Part Numbers
MP-Borhydrid 2,5 – 3,5 mmol/g (zum Herunterladen anklicken)		Reduction of carbonyl compounds, azides and oximes; reductive amination; reduction of conjugated enones to unsaturated alcohols	3 gm - 800512 10 gm - 800401 25 gm - 800402 100 gm - 800403 1000 gm - 800404 Download Material Safety Data Sheet
PS-Carbodiimid 1,0 – 1,5 mmol/g (zum Herunterladen anklicken)		Coupling agent for amide and ester synthesis, pentafluoro-phenyl, other activated ester formation	3 gm - 800508 10 gm - 800369 25 gm - 800370 100 gm - 800371 1000 gm - 800372 Download Material Safety Data Sheet
MP-Karbonat 2,5 – 3,5 mmol/g (zum Herunterladen anklicken)		General base. Neutralizes ammonium salts, scavenges acids, acidic phenols	3 gm - 800493 10 gm - 800267 25 gm - 800268 100 gm - 800269 1000 gm - 800314 Download Material Safety Data Sheet
MP-Cyanborhydrid 2,0 – 3,0 mmol/g (zum Herunterladen anklicken)		Reductive amination; reductive methylation of primary and secondary amines, reduction of amines; reduction of conjugated enones to unsaturated alcohols	3 gm - 800511 10 gm - 800405 25 gm - 800406 100 gm - 800407 1000 gm - 800408 Download Material Safety Data Sheet
PS-DES 1,0 – 1,6 mmol/g (zum Herunterladen anklicken)		Linker for alcohols, carbonyl groups, acetylenes and aromatic compounds	3 gm - 800507 10 gm - 800142 25 gm - 800143 100 gm - 800144 Download Material Safety Data Sheet
PS-DIEA 3,0 – 4,0 mmol/g (zum Herunterladen anklicken)		Tertiary amine base	3 gm - 800494 10 gm - 800279 25 gm - 800280 100 gm - 800281 1000 gm - 800312 Download Material Safety Data Sheet
PS-DMAP 1,1 – 1,8 mmol/g (zum Herunterladen anklicken)		Catalyst for acylation reactions, "Catch and Release" applications	3 gm - 800492 10 gm - 800288 25 gm - 800289 100 gm - 800290 1000 gm - 800313 Download Material Safety Data Sheet
PS-HOBt(HL) 0,9 – 1,4 mmol/g (zum Herunterladen anklicken)		Active ester reagent; coupling of acids and amines; protecting group (Fmoc, Cbz, Boc) transfer	3 gm - 800509 10 gm - 800417 25 gm - 800418 100 gm - 800419 1000 gm - 800420 Download Material Safety Data Sheet
PS-NMM 1,5 – 2,5 mmol/g (zum Herunterladen anklicken)		Tertiary amine base	3 gm - 800496 10 gm - 800282 25 gm - 800283 100 gm - 800284 1000 gm - 800318 Download Material Safety Data Sheet
PS-PPh3-Pd (zum Herunterladen anklicken)		Catalyst for Suzuki reaction, other reactions catalyzed by Pd(Ph3-Pd)4	1 gm – 800473 10 gm – 800474 25 gm – 800475 NEW! 100 gm - 800476 Download Material Safety Data Sheet
PS-TBD 1,2 – 1,9 mmol/g (zum Herunterladen anklicken)		Alkylation of phenols and amines; esterification of carboxylic acids using alkyl halides; alkylation of activate methylene compounds; dehalogenation of organic halides; high throughput synthesis of aryl triflates and aryl nonaflates; Williamson ether synthesis	3 gm - 800513 10 gm - 800421 25 gm - 800422 100 gm - 800423 1000 gm - 800424 Download Material Safety Data Sheet
MP-Triacetoxyborhydrid 1,8 – 2,4 mmol/g (zum Herunterladen anklicken)		Reductive amination with primary and secondary amines.	3 gm - 800517 10 gm - 800413 25 gm - 800414 100 gm - 800415 1000 gm - 800416 Download Material Safety Data Sheet
PS-Triphenylphosphin 2,2 mmol/g (zum Herunterladen anklicken)		Chlorination of acids and alcohols, Wittig and Mitsunobu reactions, scavenging of alkyl halides	3 gm - 800510 10 gm - 800378 25 gm - 800379 100 gm - 800380 1000 gm - 800381
PS-TsCl 1,0 – 2,0 mmol/g (zum Herunterladen Anklicken)		Loading of alcohols followed by nucleophilic displacement ("Catch and Release"), scavenging of nucleophiles	3 gm - 800490 10 gm - 800276 25 gm - 800277 100 gm - 800278 1000 gm - 800316 Download Material Safety Data Sheet
MP-TsOH 3,5 – 4,5 mmol/g (zum Herunterladen anklicken)		Scavenging and "Catch and Release" of amines, acid catalysis	3 gm - 800498 10 gm - 800461 25 gm - 800462 100 gm - 800463 1000 gm - 800464 Download Material Safety Data Sheet
MP-TsOH(65) 3,0 mmol/g (zum Herunterladen anklicken)		Scavenging and "Catch and Release" of amines, acid catalysis	3 gm - 800499 10 gm - 800478 25 gm - 800479 100 gm - 800480 1000 gm - 800481 Download Material Safety Data Sheet
MP-TsOH-Kartusche 2,5 mmol/g (zum Herunterladen anklicken)		"Catch and Release" amine purification, scavenging basic impurities, purification of compounds with basic sites.	0.5 gm resin in 6 mL cartridge, 30 per pack 800477-C30
NEU! PS-TEMPO 1-1.5mmol/g (zum Herunterladen) Download Poster 1 Download Poster 2		Oxidation of activated primary and secondary alcohols to the respective aldehydes and ketones.	3 gm - 800518 10 gm - 800482 25 gm - 800483 100 gm - 800484 1000 gm - 800485 Download Material Safety Data Sheet
ACTU Herstellung von PS-HOBt(HL) (zum Herunterladen anklicken)		active esters; coupling of acids and amines	3 gm - 800516 10 gm - 800465 25 gm - 800466 100 gm - 800467 1000 gm - 800468

PS- leicht quervernetztes Polystyrol. Leicht quervernetzte Polystyrol-Typen erfordern ein Lösungsmittel mit dem das Harz aufquellen kann, um Reagenzien an die harzgebundenen funktionellen Gruppen gelangen zu lassen. Sollte das Harz durch das Lösungsmittel nicht aufquellen, muss gegebenenfalls ein Lösungsmittel zusätzlich eingesetzt werden, um das Harz aufzuquellen, z.B. THF.

MP- hochquervernetztes, makroporöses Polystyrol. Hochgradig quervernetzte, makroporöse Harze quellen durch Lösungsmittel deutlich weniger als PS-gebundene Scavenger und Reagenzien. Ihre Effektivität ist, im Gegensatz zu den PS-gebundenen, nicht vom Quellverhalten abhängig. Um die aktiven Seiten zu erreichen, diffundieren Reagenzien durch die Porenstruktur. Daher können MP-Harze bei begrenzten Volumina, bei denen Quellen problematisch wäre, eingesetzt werden. Darüber hinaus lassen sie sich mit einer größeren Palette an Lösungsmitteln betreiben.

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