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Interim report January - June 2010
Biotage AB (publ) - disclosure notice of substantial holding of shares
Biotage appoints Anders Wikström as Vice President of Operations and Anthony Rees as Chief Scientific Officer
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Biotage are Gold Sponsors.
5th - 9th September
Copenhagen, Denmark21st - 24th September
Basel, SwitzerlandAugust 27-28
Orlando, FL10th - 12th November
Montreux, Switzerland1st - 3rd December
Barcelona, Spain
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Products for Forensic and Clinical Applications
Evaluation of Sample Preparation Methods for LC/MS that do not require Acetonitrile
Extraction of Benzodiazepines from Various Matrices using Supported Liquid Extraction (SLE) and LC-MS/MS Analysis
Extraction of Cocaine and Metabolites using Resin-based Mixed-mode Cation Exchange SPE with LC-MS/MS Analysis
Comparison of Plasma and Whole Blood Extraction using Resin-based Mixed-mode Cation Exchange SPE with LC-MS/MS Analysis
Biotage produce a range of products for use in the area of forensic toxicology and doping control in animal and human sports.
ISOLUTE® Confirm HCX Columns for High Extract Purity
ISOLUTE THC SPE Columns
ISOLUTE HM-N Supported Liquid Extraction (SLE) Columns
ISOLUTE C8, C18 and ENV+ for Doping Control Applications
ISOLUTE MFC18 for Extraction of Catecholamines from Urine
EVOLUTE ABN
ISOLUTE® Confirm HCX Columns for High Extract Purity
Extract basic drugs from biological fluids with ISOLUTE Confirm HCX mixed mode SPE columns that provide two primary retention mechanisms, non-polar (C8) and strong cation exchange. This dual retention mechanism allows a rigorous interference elution regime to be used without reducing recovery of the analytes of interest when compared to non-selective LLE, resin or C18 based methodologies. ISOLUTE Confirm HCX columns provide extremely high purity extracts of drugs of abuse from biological fluids such as urine, plasma and whole blood.
Click here for Technical details describing how to use ISOLUTE HCX sorbents
Click here for ordering information.
Download Technical Note 113 (PDF - 134 kB)
General Approach to the Extraction of Basic Drugs from Biological
Fluids using ISOLUTE Confirm HCX Mixed Mode SPE Columns
Download Technical Note 116 (PDF - 392 kB)
Generic Method for the Extraction of Basic Drugs from Biological
Fluids using ISOLUTE Mixed-mode SPE Columns and 96-well SPE Plates
Simplified Single Column Methodology for Automated Drugs of Abuse Testing
Based on the robust chemistry of ISOLUTE Confirm HCX, Biotage has developed a simple, single column approach that can be used for the extraction of all NIDA-5 (SAMHSA-5) drugs of abuse classes. The SPE methodology, designed for use with the Caliper LifeSciences RapidTrace™ uses only eight solvents in total.
For more information Download Application Note 1081
ISOLUTE THC SPE Columns
Extraction of 11-Nor-Delta-9-THC-9 carboxylic acid from urine. ISOLUTE THC columns are designed for the rapid, cost effective extraction of the THC carboxylic acid metabolite from urine prior to confirmation analysis by GC-MS. The robust procedure, based on a non-polar retention mechanism, is our method of choice for THC metabolite confirmation testing. Application Note 1001A describes the extraction of the THC metabolite from urine.
Download Application Note 1001A (PDF)
Application Note 1024 describes the extraction of the THC metabolite from urine on RapidTraceTM. Download Application Note 1024A (PDF)
Ordering Information for ISOLUTE THC SPE Columns
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Part Number |
Description |
Quantity |
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292-0005-G |
ISOLUTE THC 50 mg/10 mL |
50 |
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292-0010-B |
ISOLUTE THC 100 mg/3 mL |
50 |
ISOLUTE HM-N Supported Liquid Extraction (SLE) Columns
Supported liquid extraction is a popular approach for drugs of abuse extraction in forensic analysis. Optimized to provide high recoveries from biological fluids, ISOLUTE HM-N columns are packed with a modified form of diatomaceous earth. Designed for processing under gravity, these simple to use columns are a high productivity alternative to liquid-liquid extraction.
Click here for more information on ISOLUTE HM-N columns.
Click here for more information on the Gravity Rack for Processing ISOLUTE
HM-N Columns.
ISOLUTE C8, C18 and ENV+ for Doping Control Applications
ISOLUTE C8, C18 and ENV+ columns are ideal for applications in doping control in sport such as the extraction of steroids and their glucuronide and sulphate metabolites from human urine. For example, ISOLUTE C8 is used to extract 5 a-dihydrotestosterone from athlete’s urine (ref. Kicman et al, Clinical Chemistry, 1995, 41/11, 1617-1627).
Click here for Technical details describing how to use ISOLUTE C8, C18 and
ENV+ sorbents.
Click here for ordering information.
ISOLUTE MFC18 for Extraction of Catecholamines from Urine and Plasma
Simple SPE procedures for catecholamine extraction have been developed based on the retention of a diphenyl boronate-catecholamine complex on an ISOLUTE MFC18 SPE column. The free catecholamines are generated by treating the extract with acid.
Download Application Note 1043A (plasma) (PDF)
Download Application Note 1047A (urine) (PDF)
Download Application Note 1071A (urine) (PDF)
Click here for ordering information.
Click here for Technical details describing how to use ISOLUTE MFC18 sorbents.
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