Multisyntech Syro II Peptide Synthesizer fully automatic, computer controlled peptide synthesizer with two arm pipetting robot from Biotage.

Syro Wave™
Automated Microwave and Parallel Peptide Synthesizer

Syro Wave

Syro Wave™ Microwave and Parallel Peptide Synthesizer

The Best of Both Worlds

Rapidly synthesize high quality peptides using the microwave or parallel peptide synthesizer

The Biotage Syro Wave™ system is a programmable peptide synthesizer that is capable of both conventional room temperature parallel peptide synthesis and microwave assisted peptide synthesis. The system is a fully automated and computer controlled peptide synthesizer, based on a pipetting robot with a single arm.

The Biotage Syro Wave™ system is a combination of the MultiSynTech Syro I and Biotage Initiator 1 instruments, controlled by a single PC. This is the only system available with both microwave and parallel peptide synthesis capabilities. With the Syro Wave™ peptide synthesizer Biotage offers a system with a proven pedigree and history of performance and reliability.

Benefit from the unique ability to make part of the peptide sequence using conventional solid phase peptide synthesis on the parallel reactor block and then transfer the reactor vial to the microwave cavity to drive difficult couplings to completion.

Key Features

• Microwave assisted peptide synthesis
• Parallel peptide synthesis
• Vortex mixing in microwave cavity
• Single robotic arm
• Disposable polypropylene reactor vials
• Variable scale from 1-300 µmol
• Easy to use Syro XP software
• Separate cleavage and transfer workstation

Economically Synthesize Difficult Sequences
Use microwave irradiation and standard reagents to synthesize difficult sequences that are problematic or even impossible to synthesize using standard methods.

Save Time and Increase Productivity
Automated parallel operation allows for the synthesis of more peptides in shorter times resulting in the highest productivity. Reduce cycle times even further using microwave irradiation.

Increase Yield and Purity
Accurate dispensing of exact volumes of all reactants and vortexing of the reaction mixture, guarantee the optimal result in terms of yield and purity while minimizing waste and costs.

Detailed Reagent Calculation
The easy to use Syro XP software controls the instrument functions and calculates all amounts and volumes of amino acids and reagents required.

SyroWaveScreen

Syro XP Software

Reduce Coupling Costs

The use of a digital syringe pump and minimized flow paths lead to low amino acid and reagent consumption. This reduces coupling and running costs compared to other systems.

Optional Cleavage and Transfer Workstation

Sytem Specifications
Microwave cavity

Single robotic arm

1 x digital syringe pump, 5 mL

1 x type U-reactor block which can accept 2, 5 and 10 mL reactor vials

Choice of either: 24 or 48 position reactor block

Vortex mixer for reactor block

Separate vortex mixer for microwave cavity

Vacuum Pump

Amino Acid Rack: 32 x 50 mL Falcon Tubes

Reagent Bottle Rack: 2 x 500 mL and 3 x 200 mL

Waste Bottle: 1 x 10 liter Nalgene bottle

Includes Dell Desktop PC, Flat Panel Monitor, Printer, Syro XP Software

Dimensions (W x D x H) and Weight: 90 cm x 70 cm x 91 cm, 85 kg

Heating Process

Temperature range 40-80 ºC
Temperature increase Typically 2-5 ºC/sec
Pressure range Run at atmospheric pressure
Power range 0-200 W at 2.45 GHz, capped at 60 W during steady state
Agitation Vortex
Reactor vial sizes 2, 5 and 10 mL
Vial volume range when using the microwave unit:

2 mL reactor vial: 0.8–1.1 mL
5 mL reactor vial: 1.6–3.2 mL
10 mL reactor vial: 3.2–6.4 mL

Optional Accessories & Consumables
Disposable polypropylene reactor vials
Cleavage and Transfer Workstation
Vortex mixer for cleavage unit
24 position reactor block for 2, 5 and 10 mL reactor vials
48 position reactor block for 2 mL reactor vials

Tip synthesis module for applications that require a large number of peptides in small quantities 1-5 µmol