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Syro Wave
Automated Microwave and Parallel Peptide Synthesizer

Syro Wave

Key Features
  • Microwave assisted peptide synthesis
  • Parallel peptide synthesis
  • Vortex mixing in microwave cavity
  • Single robotic arm
  • Disposable polypropylene reactor vials
  • Variable scale from 1-300 µmol
  • Easy to use Syro XP software
  • Separate cleavage and transfer workstation

Rapidly synthesize high quality peptides using the microwave or parallel peptide synthesizer

The Biotage® Syro Wave™ system is a programmable peptide synthesizer that is capable of both conventional room temperature parallel peptide synthesis and microwave assisted peptide synthesis. The system is a fully automated and computer controlled peptide synthesizer, based on a pipetting robot with a single arm.

The Biotage Syro Wave system is a combination of the MultiSynTech Syro I and Biotage Initiator 1 instruments, controlled by a single PC. This is the only system available with both microwave and parallel peptide synthesis capabilities. With the Syro Wave peptide synthesizer Biotage offers a system with a proven pedigree and history of performance and reliability.

Benefit from the unique ability to make part of the peptide sequence using conventional solid phase peptide synthesis on the parallel reactor block and then transfer the reactor vial to the microwave cavity to drive difficult couplings to completion.

 

Economically Synthesize Difficult Sequences
Use microwave irradiation and standard reagents to synthesize difficult sequences that are problematic or even impossible to synthesize using standard methods.

Save Time and Increase Productivity
Automated parallel operation allows for the synthesis of more peptides in shorter times resulting in the highest productivity. Reduce cycle times even further using microwave irradiation.

Increase Yield and Purity
Accurate dispensing of exact volumes of all reactants and vortexing of the reaction mixture, guarantee the optimal result in terms of yield and purity while minimizing waste and costs.

Detailed Reagent Calculation
The easy to use Syro XP software controls the instrument functions and calculates all amounts and volumes of amino acids and reagents required.

SyroWaveScreen
Syro XP Software

Reduce Coupling Costs
The use of a digital syringe pump and minimized flow paths lead to low amino acid and reagent consumption. This reduces coupling and running costs compared to other systems.

 

Specifications

Microwave cavity
Single robotic arm
1 x digital syringe pump, 5 mL
1 x type U-reactor block which can accept 2, 5 and 10 mL reactor vials
Choice of either: 24 or 48 position reactor block
Vortex mixer for reactor block
Separate vortex mixer for microwave cavity
Vacuum Pump
Amino Acid Rack: 32 x 50 mL Falcon Tubes
Reagent Bottle Rack: 2 x 500 mL and 3 x 200 mL
Waste Bottle: 1 x 10 liter Nalgene bottle
Includes Dell Desktop PC, Flat Panel Monitor, Printer, Syro XP Software
Dimensions (W x D x H) and Weight: 90 cm x 70 cm x 91 cm, 85 kg

Heating Process

Temperature range:  40-80 ºC
Temperature increase:  Typically 2-5 ºC/sec
Pressure range:  Run at atmospheric pressure
Power range:  0-200 W at 2.45 GHz, capped at 60 W during steady state
Agitation:  Vortex
Reactor vial sizes:  2, 5 and 10 mL
Vial volume range when using the microwave unit:

2 mL reactor vial: 0.8–1.1 mL
5 mL reactor vial: 1.6–3.2 mL
10 mL reactor vial: 3.2–6.4 mL

Optional Accessories & Consumables

Disposable polypropylene reactor vials
Cleavage and Transfer Workstation
Vortex mixer for cleavage unit
24 position reactor block for 2, 5 and 10 mL reactor vials
48 position reactor block for 2 mL reactor vials
Tip synthesis module for applications that require a large number of peptides in small quantities 1-5 µmol

Workstation

Optional Cleavage and Transfer Workstation

Cleavage and Transfer Workstation Video Demonstration (10mb)


 

 

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