Normal-phase flash chromatography1 has been widely adopted as the method of choice for separation of product mixtures and reaction by-products. One of the most significant developments in this
area concerns the practical separation of polar molecules. Reversed-phase purification is a modification of normalphase
chromatography that provides an efficient mechanism for the separation of polar compounds.
Part No: Issued year: 2008File size: 0.14mbFile type: pdf
•Select mixed mode SPE based on functional groups present on molecule
–For basic amine containing molecules select MCX
–For molecules possessing a carboxyl group select MAX
–Easier to debug a failed extraction: pH control problem most common cause
Part No: CM-RINK-0810Issued year: 2010File size: 0.26mbFile type: pdf
Rink Amide-ChemMatrix is one of the most popular resins for for
both manual SPPS and automated SPPS, under microwave or
non-microwave conditions. For microwave synthesis, we also
recommend the use of PAL-ChemMatrix resin which can also
provide crude product in high purity.