Part No: TN0161703_02Issued year: 2017File size: 0.5mbFile type: pdf
The SPE-Z Prep manifold is a low-cost solution for disk solid phase extraction (SPE). The SPE-Z Prep manifold simultaneously processes up to 3 samples with easy-to-use rugged hardware. The multipurpose funnel (shown in Figure 1) allows easy sample loading with a variety of sample bottles and disk holder combinations on a single system. The SPE-Z Prep manifold allows the use of SPE disks instead of liquid-liquid extraction, increasing efficiency, especially since the possibility of an emulsion forming is greatly reduced.
Part No: PPS347Issued year: 2014File size: 0.49mbFile type: pdf
Trends on chemical synthesis have changed over recent years, with a more targeted approach to molecular design becoming more prevalent. As a result, the speed with which a new compound can be synthesized is key to an efficient laboratory.
Part No: F0051403_01Issued year: 2014File size: 0.14mbFile type: pdf
The Speed-Vap IV is a modern evaporation system providing safe and simultaneous unattended evaporation of up to nine pans of evaporating solvent for extractable hydrocarbons such as hexane oil and grease extractions generated using methods such as US EPA 1664, ISO 11349:2010 or Standard Methods 5520. It can also be used to evaporate solvents from extracted soil hydrocarbons and fats from foods.
Part No: TN522Issued year: 2004File size: 0.03mbFile type: pdf
Microwave assisted organic synthesis has become an important tool to medicinal chemists for rapid organic synthesis. Thousands of research papers have appeared over the last decades on the application of microwave technology in organic synthesis.1 Some of the major advantages include a spectacular decrease in reaction time, improved conversions, clean product formation and wide scope for the development of new reaction conditions.
Part No: Issued year: 2002File size: 0.36mbFile type: pdf
The first decision that needs to be made is what the final analysis will be for the analyte. This will have an impact on the sample and cartridge size, as well as the final elution solvent. Gas chromatography offers higher sensitivity than HPLC, while HPLC is better suited for ionisable species and very high molecular weights. If LC-MS is available, minimal sample clean-up may be required.
Part No: P167Issued year: 2017File size: 0.42mbFile type: pdf
For most organic and natural product chemists flash
chromatography is a necessary part of their research. As such, many chemists need quick isolation of at least one desired component from a crude mixture in relatively high yield and purity. This need for speed, purity, and yield pits these desires against each other as you can typically optimize on only two of the three goals.
In this poster, we will describe some techniques that help chemists optimize flash purification and maximize speed, yield, and purity.
Part No: P188Issued year: 2018File size: 0.33mbFile type: pdf
Herein we identified an optimized protocol
for removing an Acm protecting group using the Biotage®
Initiator+ Alstra™ and applied the protocol for a fully
automated synthesis with on-resin disulfide bond formation,
simplified with the Branches™ software feature. The results
presented herein provide a route amenable to the synthesis of
other disulfide rich peptides, greatly reducing the effort put
toward synthesizing these complex molecules.
Part No: P021Issued year: 2008File size: 1.87mbFile type: pdf
It is well known that traditional liquid-liquid extraction (LLE) provides very clean extracts prior to LC/MS analysis. Supported liquid extraction is analogous to traditional LLE, however, analyte partitioning takes place using an inert support material, rather than two immiscible liquids. This provides excellent extraction efficiencies while alleviating
many of the tedious liquid handling issues associated with LLE.
1) Remember to add stir bar for efficient mixing. Catalysts, salts, or visible precipitate should be washed clear of head space and into solution. Particles adhering to glass head space could cause excessive heating increasing possibility of failure of vial. Stay within specified vial volume range (see diagram for proper filling).
Part No: P080Issued year: 2014File size: 0.88mbFile type: pdf
This poster describes the benefits of supported liquid extraction and highlights its use in removal of endogenous matrix components that cause ion suppression/enhancement (matrix effects) in LC-MS/MS analyses.
Part No: P118Issued year: 2015File size: 0.48mbFile type: pdf
This poster examines the use of ISOLUTE SLE+ columns as an alternative to SPE for the extraction and clean up of hair samples containing drugs of abuse. SLE was found to be a simple, faster alternative to SPE for this type of analysis.
Part No: P089Issued year: 2014File size: 0.79mbFile type: pdf
This poster presents a novel method for the simultaneous extraction, derivatization and subsequent detection of both the traditional 25-hydroxy and the biologically active 1α,25-dihydroxy vitamin D metabolites in serum.