Two studies performed at Biotage labs compared the performance of Biotage® Extrahera™ automated sample processor to an equivalent manual method for extraction of β-blockers and NSAIDs (non steroidal anti-inflammatory drugs) from plasma. Significant improvements in both analyte recovery and %RSD for the analytes were observed when using Extrahera for sample processing.
For Metoprolol the %RSD improved was 19%, for Propranolol the %RSD improvement was 8%, and for Alprenolol Extrahera showed an improvement in the %RSD of 12%.
Finally - an Easy Urine Sample Preparation for LC/MS Analysis
A Smorgasbord of Analytical Methods
Extraction of Acidic Catecholamine Metabolites in Plasma Using EVOLUTE® EXPRESS ABN Prior to LC-MS/MS Analysis
Seminar: An Introduction to the Biotage Automated Workflow Solution
The 2018 Analytical Catalog is Here