This application note describes an effective and efficient ISOLUTE® SLE+ protocol optimized for 1 mL capacity formats. The simple sample preparation procedure delivers clean extracts and analyte recoveries greater than 72% with RSDs lower than 10% for all analytes.
In addition, this note describes how to achieve quantitation of all analytes down to 0.2 ng/mg of hair. This complies with the LOQ values for laboratories involved in amphetamine testing, as suggested by the Society of Hair Testing (SoHT).
New Peptide Synthesis Workflow Brochure
Extraction of Plasma Catecholamines and Metanephrines Using EVOLUTE® EXPRESS WCX SPE Prior to LC-MS/MS Analysis
New Second Generation Solvent Evaporators from Biotage
Extraction of Tobacco-Specific Nitrosamines (TSNAs) from Urine Using ISOLUTE® SLE+ Prior to UPLC/MS/MS Analysis
How to Make up to 576 Peptides in One Run