Biotage will attend the 15th International Symposium on Preparative and Industrial Chromatography and Allied Techniques.
Basel, Switzerland - October 5-8, 2014.
Don't miss the poster presentation by Dr. Ecevit Yilmaz on "Designed polymeric resins for selective separations in food and pharma".
Designed Polymers are a class of selective resins with engineered selectivities for particular target molecules or ‘classes’ of molecules. These Designed Polymers are obtained by careful design of their surface chemistry and morphology which allows them to exhibit unique separation capabilities. The tailored and optimized selectivity of Designed Resins is utilized to conduct difficult separations, to remove undesired impurities or to retrieve a valuable compound from a solution.
To solve a new separation problem, our starting point is to screen a broad library of resins. The best candidates from the library may be further modified to improve the separation. The Figure below summarizes a case study, where a novel resin with pyridine surface moieties was discovered in the library. This resin accomplishes well the separation of Penicillin G (Pen G) and its degradation products 6-aminopenicillanic acid (6-APA) and phenylacetic acid (PAA).
In this presentation, we will describe our working approach including the characteristics of Designed Polymers and their performance based on selected case studies with pharma and food ingredient examples.
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