Traditional approaches to compound purification involving chromatography utilize large volumes of toxic and expensive solvents, and significantly contribute to the environmental footprint of organizations involved in molecular research. Current directives for greener chemistry have put pressure on organizations to reduce the environmental impact of their work.
Through an understanding of the workflow of such organizations and new developments in Flash purification systems and columns, it is possible to significantly reduce the consumption and toxicity of solvents used in purifications and therefore improve the environmental impact of such research.
Biotage have made this a focus of recent developments in Flash purification and have developed a four-part approach that delivers reductions in solvent consumption of over 50%, as well as the use of substituted solvents of less environmental impact.
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