|Sample Delivery||5-mL syringe pump and/or peristaltic pump|
|Vial Size Compatibility||20 mL scintillation vial|
|30 mL scintillation vial|
|4 mL (3 variants)|
|Solvent Compatibility||Boiling points from 30°C to 160°C (to 205° when using an external vacuum pump)|
|V-10 is not suitable for solutions containing HCl at any concentration|
|Power||230VAC(±10%), 50Hz, 8A|
|110VAC(±10%), 50/60Hz, 15A|
|Gas||Compressed Nitrogen (optional) regulated up to a maximum of 2 bar|
|Dimensions (W x H x L)||40 cm x 53 cm x 48 cm (16”x21”x18.5”)|
|49 cm x 53 cm x 54 cm (19.5” x 21” x 21.5”) w. carousel|
|Weight||45 kg (100 lb)|
|50 kg (111 lb) w. carousel|
|Interfaces Connections||RS 232|
|Sample Automation||16 position Carousel|
|Liquid Handler||Gilson Liquid Handler GX271|
Tokyo based PeptiDream Inc. is a company specializing in non-standard peptide therapeutics containing non-standard amino acids, and conducts research and development of new drug candidates. PeptiDream uses the peptide synthesizers Syro I and Biotage® Initiator+ Alstra™ for the synthesis of various kinds of peptides to support drug discovery and development.
Tags: Customer Cases
User Report: V-10, Sumitomo Dainippon Pharma. Sumitomo Dainippon Pharma is recognized worldwide for its highly creative drug discovery program for treating neuropsychiatric disorders, and in specialized areas with high unmet medical needs. Its Genomic Science Laboratories installed the V-10 evaporation system in 2008, which has been used extensively for drying in-house compounds. We asked two researchers at that facility, Mr. Masahiko Ikeda and Mr. Fumitaka Nishino, about their use of the V-10 in their daily work.
Tags: Customer Cases
In order to obtain a fast synthesis of an N-unprotected tripeptide, microwave (mw) assisted deprotection, coupling and partial deprotection were applied starting with a purified protected dipeptide [Fig. 1]. The three consecutive mw assisted steps were performed without any intermediate purifications and were accomplished within some 30 minutes. The resulting crude mixture containing the Boc deprotected tripeptide ester was shown to be quite complex [Fig. 2]. The crude product was subjected to automated reversed phase flash chromatography, followed by automated fraction pooling and “thin film evaporation”. The total time for the entire procedure was 1 h 20 min. The purity of the product was > 99%.
The versatility of Biotage® V-10 enables evaporation of single samples (up to 12 mL) or large pooled volumes using V-10 pumps (syringe or peristaltic). Adding the automated vial loading/changing carousel enables unattended evaporation of up to 16 samples.
Tags: Product Notes
Tokyo based PeptiDream Inc. is a company specializing in non-standard peptide therapeutics containing non-standard amino acids, and conducts research and development of new drug candidates. PeptiDr...21 January 2014
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