Microwave irradiation is still the most effective solution for providing a fast, precise and efficient heating method for synthesizing peptides, peptoids, PNA and peptidomimetics with higher purity and yield compared to conventional synthesis methods. The Biotage® Initiator+ Alstra is a fully automated microwave peptide synthesizer with built in flexibility for both small and large scale synthesis.
Part No: PPS320.v.1Issued year: 2014File size: 0.98mbFile type: pdf
Biotage® Initiator+ Alstra™ is a fully automated, single channel, programmable microwave peptide
synthesizer for Fmoc-solid phase peptide synthesis. This instrument now comes with the Alstra 1.1
software upgrade that introduces new functionality such as Branches, Preactivation and “Edit on
the fly”, and options for UV monitoring and MAOS (organic synthesis) capability.
Part No: PPS390.V.1Issued year: 2016File size: 1.05mbFile type: pdf
Biotage® MP-Borohydride is a macroporous, solid-supported borohydride that is a solid-supported equivalent of tetraalkylammonium borohydride. The bound borohydride is a versatile reducing agent used for the reduction of carbonyl
compounds and imines, and the reductive amination of aldehydes and ketones.
Part No: PPS392.V.2Issued year: 2016File size: 1.1mbFile type: pdf
Biotage® MP-Cyanoborohydride is a macroporous polymer-supported cyanoborohydride which is a solid-supported equivalent of tetraalkylammonium cyanoborohydride. The bound cyanoborohydride can be utilized as a versatile reducing agent for the reductive amination of carbonyl compounds and reduction of imines.
Part No: PPS391.V.1Issued year: 2016File size: 1.79mbFile type: pdf
Biotage® MP-Triacetoxyborohydryde is a macroporous polystyrene-supported equivalent of tetraalkylammonium triacetoxyborohydride. MP-Triacetoxyborohydride has primary applications in the reductive amination of aldehydes and ketones under neutral or mildly acidic reaction conditions.
Part No: PPS404.V.1Issued year: 2016File size: 1.41mbFile type: pdf
PS-Benzaldehyde is the resin-bound equivalent of benzaldehyde. This resin is useful for scavenging various nucleophiles, including primary amines (selectively compared with secondary amines), hydrazines and also carbon-based nucleophiles such as Meldrum’s acid and organometallics.
Part No: PPS402.V.1Issued year: 2016File size: 0.95mbFile type: pdf
PS-Carbodiimide is a neutral, bound carbodiimide that can be used for the synthesis of amides and esters. PS-Carbodiimide may also be used for the synthesis of pentafluorophenyl (PFP) activated esters (Table 3) and N-hydroxysuccinimidyl esters
Part No: PPS393.V.1Issued year: 2016File size: 0.98mbFile type: pdf
Biotage® PS-HOBt(HL) is a sulfonamide-linked, polymersupported
equivalent of 1-hydroxybenzotriazole (HOBt). PS-HOBt(HL) is used to generate bound HOBt active esters, which can either be made and used in situ, or isolated and stored as stable intermediates.
Part No: PPS400.V.1Issued year: 2016File size: 1.3mbFile type: pdf
Biotage®PS-Isocyanate is a 1% cross-linked poly(styreneco-divinylbenzene) which has pendent benzylisocyanate functionality. The resin can readily scavenge excess nucleophiles, which are often used to drive reactions to completion.
Part No: PPS401.V.1Issued year: 2016File size: 2.11mbFile type: pdf
PS-PPh3-Pd resin is a polystyrene-supported equivalent of the small molecule catalyst tetrakis(triphenylphosphine) palladium(0) [Pd(Ph3P)4]. The primary application for the resin is as a catalyst for Suzuki-Miyaura coupling reactions between arylboronic acids and aryl halides.
Part No: PPS382.V.1Issued year: 2016File size: 1.63mbFile type: pdf
Biotage® PS-TBD is a polymer-supported base, which applications are Alkylation of phenols and amines; esterification of carboxylic acids using alkyl halides; alkylation of activated methylene compounds; dehalogenation of organic halides; high throughput synthesis of aryl triflates and aryl nonaflates; Williamson ether synthesis
Part No: PPS389.V.1Issued year: 2016File size: 2.64mbFile type: pdf
Biotage® PS-Triphenylphosphine is a diphenylphosphinated polystyrene resin that is a solid-supported equivalent of triphenylphosphine. The resin can readily convert alcohols or carboxylic acids to the corresponding chlorides or acid chlorides in carbon tetrachloride.
Part No: PPS495Issued year: 2019File size: 1.56mbFile type: pdf
When purifying molecules, maximizing your efficiency is critical
to your daily work. For us at Biotage, helping you to make the
most of your time is of paramount importance. That is why we
have designed a lean and compact automated flash system with
two column channels, so you can prepare channel two while
channel one is running.
Part No: PPS497Issued year: 2019File size: 2.55mbFile type: pdf
Biotage Sfär columns are quality tested to ensure they meet
stringent performance criteria including efficiency and peak
symmetry. Each CE-marked column is built using inert, foodgrade
plastics for lower extractables, cleaner fractions, and
packed to provide excellent resolution.
Part No: PPS568Issued year: 2019File size: 0.29mbFile type: pdf
It is important to understand there are design differences between
SNAP and Sfär Samplets, and that SNAP Samplets cannot be used on
Sfär columns and vice versa. See samplet-column compatibility table on the next page.
Part No: PPS437Issued year: 2016File size: 0.19mbFile type: pdf
Biotage® SNAP Bio flash cartridges were developed with a small
particle size (20 μm) and large pore size (300 Å) to provide
increased resolution and effective separation of complex
peptide mixtures. Depending on the quality of the peptides
synthesized, flash chromatography can be used either as the
sole method of purification or as a front end clean-up prior to
SNAP Bio offers close to prep-HPLC performance in a flash
format at a fraction of the cost
Part No: TN-0016.0108Issued year: 2008File size: 0.4mbFile type: pdf
Biotage SNAP cartridges can be used on any flash system.
The easy-to-use Luer-lok® connections do not need a
compression module to operate at 100 psi. Made from USP
Class VI materials, Biotage SNAP cartridges offer 7 types of
loading techniques including 3 internal dry loading options.
Packed to provide the highest plate count of any 50μm particle
cartridge on the market, SNAP provides increased loading
capacity and better compound separations.
Part No: TN-0025.0508Issued year: 2008File size: 0.35mbFile type: pdf
SNAP KP-NH cartridges contain amine functionalized silica.
This optimized media shields synthetic organic amines from
acidic silanols providing improved selectivity, peak shape,
purity and yield (Figure 1). Unlike traditional silica and 1°
amine (propyl amine) bonded silica, KP-NH doesn’t require the
use of chlorinated solvents or amine additives.
Part No: Issued year: 2009File size: 0.06mbFile type: pdf
SNAP flash cartridges provide several sample load options including both internal and external liquid and dry loading. This
Quick-start Guide provides sample load guidelines and loading technique suggestions, which should help you get the most
from your SNAP cartridges.
Part No: Issued year: 2008File size: 0.09mbFile type: pdf
SNAP flash cartridges provide several sample load options including both internal and
external liquid and dry loading. This Quick Start Guide provides sample load guidelines and
loading technique suggestions, which should help you get the most from your SNAP
Part No: TN-SNAP-RPC-0211Issued year: 2011File size: 1.11mbFile type: pdf
Reversed-phase flash chromatography is a very popular
purification technique using a non-polar stationary phase.
Main application areas include separation of polar, ionizable
and highly lipophilic compounds which cannot easily be
separated by normal-phase techniques.
Part No: TN-0032.0112Issued year: 2012File size: 0.75mbFile type: pdf
Precision engineered Biotage SNAP Ultra cartridges deliver double
the purification capacity utilizing small particle spherical silica with
an 40% increase in surface area. This proprietary silica reduces
peak width and provides higher concentration fractions with less
Part No: PPS447Issued year: 2017File size: 0.96mbFile type: pdf
Biotage® SPE Dry 96 and SPE Dry 96 Dual Sample Concentrators are suitable for evaporation of microplate samples across a broad range of formats. By delivering heated gas above and below each well, SPE Dry 96 systems dry samples quickly maintaining tight temperature control at user selected settings. Designed for high throughput sample processing,
SPE Dry systems have simple front panel controls and use removable gas delivery assemblies for fast adjusting and cleaning.
Part No: UI429Issued year: 2019File size: 0.18mbFile type: pdf
Peptide chemists typically use solutions containing
high percentages of trifluoracetic acid (TFA) mixed
with small volumes of various scavengers. These
solutions can be readily evaporated using Biotage®
V-10 Touch using the “Volatile” method. Despite the
presence of water and other high boiling scavengers,
this method is most efficient.