Part No: AN041-HORIssued year: 2010File size: 0.83mbFile type: pdf
This application note investigates the applicability of automated solid phase extraction using the Biotage(r) Horizon 4790 extractor and DryDisk solvent drying system to extraction of a wide range of different compounds from phenols, to triazines, to organochlorine and organophosphorous pesticides spiked into tap water at a concentration of 1 ug/L.
Part No: Issued year: 2014File size: 0.34mbFile type: pdf
In this poster, an IONICS 3Q 220 triple quadrupole mass spectrometer using a load, wash, elute method protocol with recently advanced solid phase extraction (SPE) sorbent technology (EVOLUTE EXPRESS WCX) was used to perform analysis of the two compounds. As a result low levels of metanephrine and normetanephrine are detectable in plasma with short sample preparation and LC run times. This LC-MS/MS method provides a fast, sensitive, accurate, and reproducible solution for the analysis of ME and NME in plasma.
Part No: AN303Issued year: 2007File size: 0.14mbFile type: pdf
Heck reactions utilizing a thermostable catalyst in combination with microwave irradiation have been performed. A substantial enhancement of reaction rates as well as excellent regiocontrol could be obtained under microwave conditions without using inert gas. A slight increase in yield was also noted.
Part No: CM-HMPB-0810Issued year: 2010File size: 0.29mbFile type: pdf
For peptides acid, we recommend using the HMPB-ChemMatrix
as this resin will provide high crude purity and a recovery yield of
90-95%. The Wang-ChemMatrix will produce similar crude
peptide purity, but the recovery yield is lower (60-70%). On
request, we can provide preloaded HMPB-ChemMatrix resins with
all 20 naturally occurring amino acids. Other amino acids can be
preloaded on special request.
Part No: PPS535Issued year: 2017File size: 0.8mbFile type: pdf
When a new piece of equipment is introduced the question is always raised about performance. Does it perform as well as its predecessor? What about the performance over time? This technical note will provide data to describe the performance of the SPE-DEX 5000, providing solid phase disk extraction (SPE), compared to standards required by environmental methods.
Part No: PPS538.V.1Issued year: 2015File size: 0.29mbFile type: pdf
The quality of the solid phase disk used for extraction is key to the success and ease of an analysis. Horizon Technology’s Pacific™ Premium Oil & Grease SPE disks for Method 1664/ISO 11349 meet all Initial Precision and Recovery (IPR), Method Detection Limit (MDL) and Ongoing Precision and Recovery (OPR) limits specified by the US EPA, while saving the lab extraction time and solvent volume. Both 47 and 100-mm disks are fast-flowing and have a high-retention capability, which increases efficiency without compromising recoveries.
Part No: UI402Issued year: 2019File size: 0.36mbFile type: pdf
Confidence is what you need before you separate your precious
compound on a new brand of flash chromatography column.
Predictably getting your compound in a pure state is what you
want, and if you can get it faster and use less solvent all the
better. After all, your project needs to be completed on time,
and trying something new is not always appealing.
In order to take your first steps toward gaining that confidence
you can follow the same procedures we use here at Biotage to
Part No: AN747Issued year: 2011File size: 0.18mbFile type: pdf
Biotage® PRESSURE+ manifolds deliver positive pressure, parallel processing for 96 well plates and column formats. The systems utilize a consistent, uniform flow of positive pressure to move both low and high viscosity liquids through SPE plates and columns. ISOLUTE SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation and greatly matrix effects associated with biofluid analysis.
SLE+, SLE, Supported Liquid Extraction, positive pressure manifold, Pressure+96, Pressure+48
Part No: UI333Issued year: 2015File size: 0.89mbFile type: pdf
If high back pressure is detected in the makeup pump lines, and/or the High Makeup Flow Pressure dialog appears, the microfilter may be partially clogged and needs replacing. This is a step by step guide.
Part No: UI403Issued year: 2019File size: 0.13mbFile type: pdf
Biotage® Sfär columns can be used with CombiFlash Rf and
CombiFlash NextGen Systems. This document outlines how to
set up your CombiFlash instrument for use with Biotage® Sfär
Silica HC and Biotage® Sfär C18.
Part No: UI319.v3Issued year: 2017File size: 0.7mbFile type: pdf
Biotage®SNAP Ultra cartridges are compatible with CombiFlash® Rf Systems. As a convenience, Biotage SNAP Ultra cartridges with Luer slip connectors are available. Contact your Biotage representative for ordering information.