Part No: AN908.V.1Issued year: 2014File size: 1.33mbFile type: pdf
The removal of interferences and sample concentration are
essential steps in trace level detection of pesticides, sheep
dips, herbicides and PCBs in river water, wastewaters and
trade effluents. The following methods were developed by
the Environment Agency National Laboratory Service facility
at Nottingham using the Biotage RapidTrace for automated
solid phase extraction and the TurboVap II for evaporation.
The procedures are UKAS accredited and can reach detection
limits of 0.001 ug/Litre for some compounds.
Part No: AN904.V1Issued year: 2014File size: 1.33mbFile type: pdf
EPA methods 8260 & 8270 cover the analysis of polychlorinated
dibenzo-p-dioxins and polychlorinated dibenzofurans
in ground & surface waters. This also now includes
1,4-dioxane and PCBs. This application note will focus on
the automated SPE of the sample rather than the detection
which usually involves GCMS or LCMS. NB The columns
and reagents used for soils and sediment analysis differ to
ground water extraction.
Part No: AN905Issued year: 2010File size: 0.25mbFile type: pdf
The extraction and segregation of Organic compounds from core samples taken from marine sediments is used to predict climate conditions, reconstruct sea temperatures and identify the type of vegetation from the C3 ( Temperate cli-mate) and C4 ( Tropical Climate) isotopic mass spectroscopy ratio analysis.
Part No: AN120-HORIssued year: 2017File size: 1.44mbFile type: pdf
Polycyclic aromatic hydrocarbons (PAHs) can be found in a number of water types, such as drinking water, surface water, ground water and wastewater. There are serval types of extraction techniques that can be implemented to remove them from water for measurement including liquid-liquid extraction (LLE), continuous liquid-liquid extraction (CLLE) and solid phase extraction (SPE). With LLE and CLLE there is little selectivity within the methods for difficult matrices or other compound interferences.
Part No: AN906.V.1Issued year: 2014File size: 1.29mbFile type: pdf
With the widespread clinical use of antidepressant drugs comes the need to accurately measure therapeutic lev-els to determine proper dosage, as well as check for toxic levels and patient compliance. More and more laboratories are shifting their therapeutic drug monitor-ing from liquid extraction to solid phase extraction. A large clinical laboratory has automated the process of extracting these drugs from serum using the RapidTrace SPE Workstation.
Part No: AN002-HORIssued year: 2015File size: 0.94mbFile type: pdf
This study shows that the Biotage® 4790 Automated Extractor system, along with the Atlantic™ DVB disk, the DryDisk® separation membrane, and the DryVap® Concentrator System can be successfully used to analyze for Nonyl Phenol and Bisphenyl A in water samples. This sample preparation process is fully automated, requiring minimal human intervention, and allowing for reductions in sample processing costs.
Part No: RP-DS-04Issued year: 2010File size: 0.19mbFile type: pdf
When analyzing human urine for drugs of abuse, one of the most common tests is for the cocaine metabolite Benzoylecgonine (BZE). A contract laboratory has automated this labor intensive procedure using the RapidTrace.
Part No: P101Issued year: 2014File size: 0.4mbFile type: pdf
Using the TLC to step gradient is simple and fast requiring only a minute or so to enter the data into the Isolera and create the method. The methods are scalable to larger cartridges increasing purification savings even more.
Part No: AN094Issued year: 2014File size: 1.03mbFile type: pdf
Synthesis of branched peptides is very challenging. Here we show the synthesis of a complex multi-branched peptide and how this process can be simplified using Branches™.
Part No: AN093.v2Issued year: 2014File size: 0.67mbFile type: pdf
We demonstrate the capability of the Biotage® Initiator+ Alstra™ microwave peptide synthesizer to fully automate the on-resin synthesis of cyclic peptides with examples showing disulfide bridge formation and side-chain to side-chain cyclization respectively.
Part No: P063Issued year: 2014File size: 0.33mbFile type: pdf
This poster describes the automation of a method for extraction of ochratoxin A from red wine using ISOLUTE Myco SPE columns on the RapidTrace workstation.
Presented at Pittcon 2014, Chicago, USA.
Part No: PPS387Issued year: 2015File size: 1.32mbFile type: pdf
This guide describes simple practical strategies, hints and tips designed to mitigate or avoid cross-well contamination or ‘cross talk’ in high throughput 96-well based sample preparation techniques.
Part No: TechTipIssued year: 2011File size: 0.12mbFile type: pdf
This month’s topic of discussion will be on the drying capability of the
DryVap® Concentrator System. The focus will be on how to properly dry
your extracts and what to avoid.
Part No: P175Issued year: 2018File size: 2.14mbFile type: pdf
This poster presents a method for detection of approximately 100 drugs and metabolites in urine using mixed-mode polymeric cation exchange solid phase extraction (SPE).
Four different glucuronidase enzymes and several incubation times and temperatures were evaluated to determine optimum hydrolysis conditions for seven commonly detected glucuronide metabolites. Samples were subjected to offline hydrolysis and SPE (EVOLUTE® EXPRESS CX, Biotage, Charlotte, NC) and results compared to an SPE plate that incorporates in-well hydrolysis (EVOLUTE HYDRO CX, Biotage).
MSACL 2018, Palm Springs, CA
Part No: BIOMARK97.6Issued year: 2019File size: 0.13mbFile type: pdf
this document is released to communicate that the part numbers included in the letter are impacted by a phase out, replacement or significatnt price change
Part No: PPS470Issued year: 2018File size: 0.06mbFile type: pdf
Factory Service Agreement
SER-XXX-SAF
Biotage will provide the following services based upon the
terms and conditions set forth in the agreement quotation.
Part No: PPS480Issued year: 2018File size: 0.06mbFile type: pdf
First Year Maintenance Plan
SER-XXX-FYMP
Biotage will provide the following services based upon the
terms and conditions set forth in the agreement quotation.
The definitive guide to flash chromatography. This document presents in detail the broad selection of ways that materials for purification can be loaded onto a flash cartridge.
This brochure presents the extensive range of instrumentation for flash purification from Biotage. To complement these products Biotage also offers a complete range of flash consumables, including columns in a variety of sizes packed with irregular and spherical silica, making Biotage your one-stop partner for your flash purification needs.
Keywords: Isolera™ Dalton, Isolera™ Spektra, 10 Isolera™ Spektra One and Four, Isolera™ Spektra LS (Large Scale), Isolera™ Prime, Isolera™ ELSD-1080, Biotage® Flash 75/150, Biotage® Flash 400
Part No: BiotHR1Issued year: 2017File size: 0.15mbFile type: pdf
This statement sets out Biotage’s actions to understand all potential modern slavery risks related to its business and to put in place steps that aim at reducing the risk of slavery or human trafficking occurring within in its own business and its supply chains. This statement relates to actions and activities during the financial year 1 Jan 2016 to 31 December 2016.
Part No: PPS465Issued year: 2018File size: 0.07mbFile type: pdf
Limited Service Agreement
SER-XXX-SAL
Biotage will provide the following services based upon the
terms and conditions set forth in the agreement quotation.
Part No: PPS377.V.1Issued year: 2016File size: 1.13mbFile type: pdf
Biotage® Metal Scavenging Toolkit is an essential tool that can enable you to quickly and efficiently find the right metal scavenger for your application. It contains protocols, guidance and recommendations for working in batch mode or passing solutions through a fixed bed, this all in one kit showcases the metal scavengers and provides practical information on how to use the metal scavengers in your application for the best results.
Part No: PPS471.v1Issued year: 2018File size: 0.07mbFile type: pdf
Performance Maintenance Plan
SER-XXX-PMP
Biotage will provide the following services based upon the
terms and conditions set forth in the agreement quotation.
Part No: PPS464Issued year: 2018File size: 0.07mbFile type: pdf
Priority Service Agreement
SER-XXX-SAP
Biotage will provide the following services based upon the
terms and conditions set forth in the agreement quotation.
Part No: PPS330.v3Issued year: 2016File size: 0.37mbFile type: pdf
With a Biotage Service Agreement you avoid unexpected expenses and order administration for service visits. Biotage systems covered by a Service Agreement receive priority service attention.
Part No: PPS458Issued year: 2017File size: 1.04mbFile type: pdf
On Aug 30, 2017 a scientific literature search for the keywords Biotage AND peptide
was performed by Biotage personnel. The search identified 5380 peer-reviewed
publications from the global community, excluding patents and simple citations.
Below are approximately 100 titles illustrating the breadth and depth of research in
which Biotage tools are utilized.
Biotage operates a simple support policy - we commit
to fully support all new instruments from the date of
installation to the System Support Commitment date
(SSC), which is a period of up to 7 years.
Part No: PPS381Issued year: 2015File size: 1.07mbFile type: pdf
The versatility of Biotage® V-10 enables evaporation of single samples (up to 12 mL) or large pooled volumes using V-10 pumps (syringe or peristaltic). Adding the automated vial loading/changing carousel enables unattended evaporation of up to 16 samples.
Part No: PPS534.V.1Issued year: 2017File size: 0.97mbFile type: pdf
The SPE-Z Prep manifold is a low-cost solution for disk solid phase extraction (SPE). The SPE-Z Prep manifold simultaneously processes up to 3 samples with easy-to-use rugged hardware. The multipurpose funnel (shown in Figure 1) allows easy sample loading with a variety of sample bottles and disk holder combinations on a single system. The SPE-Z Prep manifold allows the use of SPE disks instead of liquid-liquid extraction, increasing efficiency, especially since the possibility of an emulsion forming is greatly reduced.