Part No: T63Issued year: 2010File size: 0.07mbFile type: pdf
When not in use, the check valve ball can stick, preventing the elution of solvents into the
collection vessel. Prior to beginning an extraction, free the Check Valve by using the Check
Valve Tool (PN: 02-0725 for the 1000/3000XL Extractors, or PN: 02-0727 for the 4790
Part No: T38Issued year: 2009File size: 0.06mbFile type: pdf
The Bleed Valve Assembly is provided to control the level of vacuum applied to the Extractor. This
Tech Tip provides instructions on installing the Bleed Valve Assembly on the Horizon Technology
Part No: PPS347Issued year: 2014File size: 0.49mbFile type: pdf
Trends on chemical synthesis have changed over recent years, with a more targeted approach to molecular design becoming more prevalent. As a result, the speed with which a new compound can be synthesized is key to an efficient laboratory.
Part No: F0051403_01Issued year: 2014File size: 0.14mbFile type: pdf
The Speed-Vap IV is a modern evaporation system providing safe and simultaneous unattended evaporation of up to nine pans of evaporating solvent for extractable hydrocarbons such as hexane oil and grease extractions generated using methods such as US EPA 1664, ISO 11349:2010 or Standard Methods 5520. It can also be used to evaporate solvents from extracted soil hydrocarbons and fats from foods.
Part No: TN522Issued year: 2004File size: 0.03mbFile type: pdf
Microwave assisted organic synthesis has become an important tool to medicinal chemists for rapid organic synthesis. Thousands of research papers have appeared over the last decades on the application of microwave technology in organic synthesis.1 Some of the major advantages include a spectacular decrease in reaction time, improved conversions, clean product formation and wide scope for the development of new reaction conditions.
Part No: P215Issued year: 2020File size: 0.34mbFile type: pdf
Peptides are well suited for use as tool compounds to interrogate biological systems and processes due to their chameleonic ability to mimic a potential protein partner within the biological system of interest. Their use in this application continues to grow as the rules governing permeability across the plasma membrane are further elucidated. Unfortunately, a well-defined secondary structure is often required for productive interaction with the other protein partners within the system of interest. ACS, Spring, 2020
Part No: Issued year: 2002File size: 0.36mbFile type: pdf
The first decision that needs to be made is what the final analysis will be for the analyte. This will have an impact on the sample and cartridge size, as well as the final elution solvent. Gas chromatography offers higher sensitivity than HPLC, while HPLC is better suited for ionisable species and very high molecular weights. If LC-MS is available, minimal sample clean-up may be required.
Part No: PPS618Issued year: 2020File size: 1.91mbFile type: pdf
Load-Wash-Elute SPE, eliminating conditioning and equilibration steps can provide excellent extraction performance while reducing complexity and processing time. Elimination of the evaporation step using microelution SPE can also bring significant time savings.
Part No: P210Issued year: 2019File size: 0.56mbFile type: pdf
This poster evaluates two “pass through” solid phase extraction techniques: (protein removal/phospholipid depletion (ISOLUTE PLD+) and dual mode extraction (ISOLUTE HYDRO DME+)) and supported liquid extraction (ISOLUTE SLE+) for a group of about 100 drugs of abuse compounds in whole blood.
Part No: P167Issued year: 2017File size: 0.42mbFile type: pdf
For most organic and natural product chemists flash
chromatography is a necessary part of their research. As such, many chemists need quick isolation of at least one desired component from a crude mixture in relatively high yield and purity. This need for speed, purity, and yield pits these desires against each other as you can typically optimize on only two of the three goals.
In this poster, we will describe some techniques that help chemists optimize flash purification and maximize speed, yield, and purity.