This application note details effective protocols for optimized for loading volumes of either 400 μL or 1 mL. The simple sample preparation procedure delivers clean extracts and analyte recoveries ranging from 85–99% with RSDs below 10% for all analytes.
ISOLUTE® SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation, and significantly reduced sample preparation.
Cocaine, AEME, EME, Benzoylecgonine, Cocaethylene and Norcocaine.
Typical analyte % recoveries for extracted cocaine and metabolites from urine (n=7) using the described ISOLUTE® SLE+ protocol.
Update on Biotage’s COVID-19 Response Plan
Smarter Sample Preparation for Environmental Challenges
How does Biotage Act in the Corona Virus Situation?
Sample Preparation Techniques for Synthetic Benzodiazepines
Good Laboratory Practices Software Upgrade for Biotage® Extrahera™