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Extracting Drugs of Abuse from Whole Blood Just Got Easier

29 February 2016

Biotage Labs have released a suite of six application notes describing extraction of various drugs and metabolites from whole blood using a supported liquid extraction protocol. 


Whole blood is traditionally a difficult matrix to work with. These application notes demonstrate the ease of processing whole blood samples using ISOLUTE® SLE+ columns. A separate application note addresses each of the main classes of drugs of abuse (opiates, barbiturates, benzodiazepines, amphetamines and  cocaines) containing optimized extraction, derivatization and GC-MS analytical conditions for each. In addition, conditions for simultaneous extraction of all classes for screening applications is included.


  • Opiates
  • Barbiturates
  • Benzodiazepines
  • Amphetamine
  • Cocaine
  • Buprenorphine
  • Norbuprenorphine

Download the application notes below

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ISOLUTE® SLE+ Supported Liquid Extraction