Structural and functional studies of membrane proteins remain a challenge due to difficulties in their handling. The combination of using high concentrations of reagents (0.5M) and fast and precise microwave heating to increase the coupling efficiency using the Biotage® Initiator+ Alstra™ microwave peptide synthesizer, enabled the efficient synthesis of peptide ‘18A’ and simplified the subsequent purification by RP-HPLC despite its relatively low solubility, to afford the desired peptide in 52% yield (468 mg). Read the full application note using the link below.
Update on Biotage’s COVID-19 Response Plan
Smarter Sample Preparation for Environmental Challenges
How does Biotage Act in the Corona Virus Situation?
Sample Preparation Techniques for Synthetic Benzodiazepines
Good Laboratory Practices Software Upgrade for Biotage® Extrahera™