Our carefully selected portfolio of industrial scale products have a proven track record of successful applications and use in scale-up projects. We can support the discovery, development and manufacturing of customer pharmaceutical and biotechnology products, from pre-clinical, phase I, II and III to small scale commercial operations.
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Biotage® MP-Isocyanate is a macroporous polystyrene-bound scavenger, for nucleophiles such as amines and alkoxides.
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I need to remove counter ion from peptidic molecules. Can I use PS-Trisamine to achieve this?
This will depend on the counter ion and peptide in question, and the state of protection/deprotection. A couple of scenarios are:
1) If the goal is to remove anions from a cationic peptide structure, then PS-Trisamine will only work in organic solvents.
2) If the solvents are aqueous or non-swelling, then MP-Trisamine may be useful. The better solution is Si-Carbonate or MP-Carbonate.
3) If the goal is remove cationic from a anionic peptide structure, then SCX-2 or MP-TsOH would be more helpful.Browse more questions and answers >