Biotage® PS-PPh3-Pd resin is a polystyrene-supported equivalent of the small molecule catalyst tetrakis(triphenylphosphine) palladium(0) [Pd(Ph3P)4]. The primary application for the resin is as a catalyst for Suzuki-Miyaura coupling reactions between arylboronic acids and aryl halides. PS-PPh3-Pd may also have applications in other types of palladium-catalyzed processes in which Pd(Ph3P)4 is used. The Suzuki reaction is one of the most widely practiced coupling protocols for the preparation of symmetrical and unsymmetrical biaryl compounds. The resin was developed to perform in a manner similar to that of the well-established catalyst, while facilitating reagent handling and simplifying workup, product isolation, and removal of palladium.
Part No. | Description | Pack Size | |
---|---|---|---|
800473 | Biotage® PS-PPh3-Pd, 1 g | 1 | Add to quote |
800474 | Biotage® PS-PPh3-Pd, 10 g | 1 | Add to quote |
800476 | Biotage® PS-PPh3-Pd, 100 g | 1 | Add to quote |
800475 | Biotage® PS-PPh3-Pd, 25 g | 1 | Add to quote |
Key facts and figures and quick at a glance usage data
For over 15 years Biotage has been guiding and leading the industry in supported reagents and scavengers. Biotage® PS-PPh3-Pd resin is a polystyrene-supported equivalent of the small molecule catalyst tetrakis(triphenylphosphine) palladium(0) [Pd(Ph3P)4].
More effective than traditional methods, polymer supported chemistry has been used widely in applications for over fifty years. Biotage supported reagents and scavengers are based on functionalized polystyrene or silica polymers and are 100% insoluble, therefore can be added to reactions and completely removed afterwards. The primary application for the resin is as a catalyst for Suzuki-Miyaura coupling reactions between arylboronic acids and aryl halides.
Key supplier to industry for over 15 years, used in numerous patents and cGMP process campaigns
From grams in research through to multi kilogram quantities in production campaigns. In general. This resin was developed to perform in a manner similar to that of the well-established catalyst, while facilitating reagent handling and simplifying workup, product isolation, and removal of palladium.
Inert, specifically-reactive and deployed to achieve a specific purpose. With lot control, QA / QC documentation, SDS, ISO 9001 / 14001 registration, BSE / TSE statement, shelf-life statement, these resins also support the audit trail.
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