Early phase small animal drug trials have largely been the driver for miniaturization due to limited sample size. However, this trend is gaining popularity in forensic/clinical toxicology with respect to alleviating patient discomfort, particularly in pediatrics. This
combination along with increased LC-MS/MS sensitivity has been invaluable in reigniting focus within the low volume sample preparation area. This poster will present an automated approach for low volume solid phase extraction (SPE) and its application
within the clinical and forensic toxicology arenas.
Literature number: P236.V.1