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In peptide purification, mobile-phase acidity (available solution protons) strongly influences peptide charge-state distribution, retention, and separation selectivity. Trifluoroacetic acid (TFA) is w...
Introduction Flash chromatography remains a cornerstone purification technique across pharmaceutical, academic, and industrial chemistry workflows due to its speed, scalability, and robustness.1 Perfo...
The rapid expansion of biologics discovery – from high-throughput antibody screening to the development of viral vectors for gene therapy – has created an unprecedented demand for high-quality, transf...
QuEChERS is a sample preparation technique commonly used in food safety testing for pesticide residue analysis. This two-stage extraction and clean-up technique was developed to streamline sample proc...
Introduction Patulin is a mycotoxin produced by aspergillum and penicillium mold species commonly found on rotting apples. Although not a particularly potent toxin, patulin has been shown to be genoto...
Introduction The method described in this application note achieves high recoveries of acrylamide in fried potato chips (crisps). The method is sensitive enough to measure levels as low as 10 ppb in a...
Introduction The method described in this application note achieves high recoveries of acrylamide in coffee. The method is sensitive enough to measure levels as low as 1 ng/mL in coffee (solution), 25...
Molasses is commonly used in equine feed manufacturing as a palatability enhancer or feed binder. However, it may occasionally be contaminated with pharmacologically active substances. Tramadol, a syn...
Extraction protocols and analytical methods have been utilized and revised for detecting Per-and Polyfluoroalkyl Substances (PFAS) in aqueous matrices since 2013. The toxicity and persistence of PFAS ...
Automated sample preparation offers significant advantages for diagnostic laboratories performing assays with high sample loads and labor-intensive manual steps. At Semmelweis University in Hungary, t...