The introduction of parallel synthesis in pharmaceutical R&D has resulted in the need for purification systems that allow for increased throughput. With reactions being carried out in a microplate footprint, it is important that the reaction workup can also be performed in this way. When using the 96-well format, there are limitations on both the reaction scale and also the sorbent capacity for the purification step. Using a 24-well system allows for greater sorbent masses to be utilized, increasing the scale of purification.
Literature number: PPS597