---
title: ISOLUTE® FILTER+ high performance filtration plates FAQ
description: ISOLUTE® FILTER+ plates provide effective, workflow friendly filtration of biological samples, and are ideal for use with urine prepared by ‘dilute and shoot’.
---

[Literature ](https://www.biotage.com/literature)

# [ISOLUTE® FILTER+ high performance filtration plates FAQ](https://www.biotage.com/literature/technical-note/isolute-filter-high-performance-filtration-plates-faq)

 Written by [Biotage](https://www.biotage.com/literature/author/biotage) | Dec 6, 2025 8:37:43 AM

ISOLUTE® FILTER+ plates provide effective, workflow friendly filtration of diverse biological samples, and are ideal for use with urine prepared by ‘dilute and shoot’ prior to UPLC-MS/MS analysis. ISOLUTE FILTER+ plates are designed to prevent sample particulates from reaching the analytical UPLC column, protecting the analytical system from particulate build up over time. Increased back pressures due to particulate accumulation necessitate frequent downtime for replacement or regeneration of the expensive analytical column. 

Literature number: PPS452

[View full post](https://www.biotage.com/literature/technical-note/isolute-filter-high-performance-filtration-plates-faq)

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