When it comes to chromatography, no two media are the same. Silica from one flash column manufacturer will likely be different from another due to their media source’s manufacturing process and raw material quality. The same is true with bonded silica
such as C18. Some flash column suppliers buy C18 bonded silica from a chromatography media supplier while others, such as Biotage, synthesize their own flash C18 media, and thus offer better control quality, performance, and eliminate supply issues.
Literature number: PPS707