Automating Forensic Toxicology Workflows

The Biotage® Lysera system facilitates fast sample pulverization of solid matrix whilst simultaneously extracting the analyte of interest from the matrix.

The system is specifically designed for the grinding, lysing and homogenization of samples prior to any form of sample extraction. Using sample tubes pre-filled with a variety of beads, the Lysera vigorously and uniformly shakes the tubes providing an efficient, consistent, high-yield and quality homogenization usually in less than 40 seconds. Samples are enclosed in individual vessels to prevent cross contamination and can accommodate dry or wet homogenization of samples from milligram to gram quantities.

The Extrahera™ family automated sample preparation workstations allow rapid and efficient cartridge and/or plate extractions to a high level of accuracy and precision.

The Extrahera™ Classic is a powerful system for SPE, SLE, PLD and PPT based methods, in both plate and column formats.

The Extrahera™ LV-200 is dedicated to 96-well arrays for microelution technologies and classical 96-well SPE, SLE, and PPT or PLD consumable formats.

The Extrahera™ HV-5000 is dedicated to column-based sample prep with support for classical 3-, 6-, 10- and 15-mL SPE and SLE column consumable formats.

Choosing the right approach for every assay depends on a multitude of factors, including analyte(s), matrix type, analytical methodology, speed, cost per sample, extract cleanliness and sensitivity requirements and throughput needs. Biotage® offers a plethora of consumables so you can pick the one that fits your assay's needs. The following are some of the recommended options for forensic toxicology applications:

ISOLUTE® SLE+ plates and columns are designed to provide stress free extraction of analytes from biological fluids, with high analyte recoveries, and clean, protein and phospholipid free extracts

ISOLUTE® HCX is a mixed-mode sorbent providing clean extracts for basic compounds from complex biological fluid samples using a dual retention mechanism

EVOLUTE® EXPRESS ABN is a modified PS-DVB polymeric SPE phase for extraction of acidic, basic and neutral analytes

ISOLUTE® C18 is a retentive, non-polar sorbent for extraction of a range of analytes from aqueous samples using a non-polar retention mechanism

The TurboVap® tube evaporators are designed around a common chassis with interchangeable accessories, allowing users to switch quickly between configurations for a wide range of sample sizes and applications.