ISOLUTE® HCX
Solid-phase extraction cartridges and plates
A mixed-mode sorbent providing clean extracts for basic compounds from complex biological fluid samples using a dual retention mechanism.
ISOLUTE® HCX combines non-polar and strong cation exchange retention mechanisms to isolate basic analytes from complex aqueous matrices such as urine and plasma. ISOLUTE® HCX is the most commonly used sorbent for extraction of drugs of abuse from biological fluid samples. A number of application notes describing the extraction of common drugs of abuse classes are available.
Specifications
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Chemical description
Octyl (C8, non-end capped) and sulfonic acid (SO3-)
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Sorbent type
Mixed-mode (non-polar and strong cation exchange)
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Average particle size
50 µm
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Pore diameter
60 Å
Resources
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Download
Product note
QuickStart guide to SPE
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Download
Technical note
Sample preparation by mixed-mode SPE using ISOLUTE® HCX
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Download
Technical note
General approach to the extraction of basic drugs from biological fluids using ISOLUTE® HCX mixed-mode SPE cartridges
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Read article
Application note
Sample preparation for fentanyl analogues in whole blood
Ordering information
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