Literature

Biotage® Oligo SPE solution for bioanalysis of therapeutic oligonucleotides

Written by Biotage | Dec 6, 2025 9:30:43 PM

Biotage® Oligo SPE is a solid-phase extraction (SPE) solution specifically developed for efficient extraction of oligonucleotide-based therapeutics from biological samples, including plasma, serum, urine and tissue homogenates. Using mixed-mode weak anion exchange (WAX) chemistry, Biotage® Oligo SPE effectively removes interfering proteins, salts, sugars, lipids and DNA fragments. Its tailored sorbent design delivers clean extracts and consistently high recoveries across a variety of oligonucleotide structures and chemistries.

Literature number: PPS769