Biotage® Oligo SPE solution for bioanalysis of therapeutic oligonucleotides

By Biotage

Biotage® Oligo SPE is a solid-phase extraction (SPE) solution specifically developed for efficient extraction of oligonucleotide-based therapeutics from biological samples, including plasma, serum, urine and tissue homogenates. Using mixed-mode weak anion exchange (WAX) chemistry, Biotage® Oligo SPE effectively removes interfering proteins, salts, sugars, lipids and DNA fragments. Its tailored sorbent design delivers clean extracts and consistently high recoveries across a variety of oligonucleotide structures and chemistries.

Literature number: PPS769

Published: Dec 6, 2025 10:30:43 PM

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