--- title: Doping Control Sample Preparation description: Biotage sample preparation applications and products for doping control laboratories. --- CLOSE × Doping Control Sample Preparation CAT_ANA_APP_DOPING_v2 # Doping Control Sample Preparation Biotage develop sample preparation products that solve the daily challenges faced by anti-doping labs.  We understand your need to reduce matrix effects in LC-MS/MS, without compromising speed, simplicity or analyte recovery in your sample preparation.   With the increasing use of automation in sample preparation, we focus reliable, easily automated techniques and procedures which can maximize the use of automated extraction systems. Learn more about our smart sample preparation solutions and find lots of useful resources for doping applications in the sections below. ![AdobeStock_312822563](https://www.biotage.com/hs-fs/hubfs/ANALYTICAL/IMAGES/CATALOG/PRODUCT%20PAGES/AdobeStock_312822563.jpeg?width=780&name=AdobeStock_312822563.jpeg) #### [White paper: Current methodologies for drugs of abuse urine testing](https://www.biotage.com/documents/current-methodologies-doa-urine-testing-white-paper?hsLang=en) #### [Blog: Methods for a drug class or one large panel - what's the difference](https://www.biotage.com/blog/methods-for-a-drug-class-or-one-large-panel-whats-the-difference) #### [Blog: Automating sample prep boosts analytical lab efficiency](https://www.biotage.com/blog/automating-sample-prep-boosts-analytical-lab-efficiency) #### [Avoiding cross talk in 96-well based sample preparation](https://www.biotage.com/documents/avoiding-cross-talk-96-well-based-sample-preparation-brochure?hsLang=en) Human Blood & Urine Testing Equine Testing ## Human Blood & Urine Testing APPLICATION NOTE [ Automated Extraction of Drugs of Abuse Panel from Urine ](https://www.biotage.com/documents/automated-extraction-doa-panel-human-urine-isolute-sle-biotage-extrahera-hv-5000?hsLang=en) This application note describes the automated extraction of 44 drugs of abuse from human urine using 1 mL sample capacity ISOLUTE® SLE+ supported liquid extraction columns prior to LC/MS-MS analysis. APPLICATION NOTE [ Human Steroids in Serum ](https://www.biotage.com/documents/extraction-comprehensive-steroid-panel-human-serum-isolute-sle?hsLang=en) This application note describes the extraction of a panel of steroid hormones from human serum prior to LC/MS-MS analysis. The simple sample preparation procedure delivers clean extracts and high, reproducible recoveries for all analytes in the range 5–5000 pg/mL.   APPLICATION NOTE [ Steroid Panel in Urine ](https://www.biotage.com/documents/extraction-comprehensive-steroid-panel-human-urine-evolute-express-abn?hsLang=en) This method describes a simple approach for the extraction of a panel of endogenous steroids and metabolites from human urine samples. The method is easy to automate, and deliver high, reproducible recoveries, with excellent LOQs in the low pg/mL range for many analytes.   BLOG [ Synthetic Benzodiazepines…..there’s more than just Opioids to test for ](https://www.biotage.com/blog/synthetic-benzodiazepines-theres-more-than-just-opioids-to-test-for) We’ve all heard about Synthetic Opioids and how frequently they’re being abused, creating an Opioid Epidemic. What many of us aren’t hearing about are other synthetic compounds that are out there. WEBINAR [ Opioids: Choosing the Best Solution for Your Laboratory ](https://www.biotage.com/opioids-choosing-the-best-solution-for-your-laboratory-on-demand-webinar) More documents ## Equine Testing APPLICATION NOTE [ Steroid Panel from Horse Hair ](https://www.biotage.com/documents/extraction-comprehensive-steroid-panel-horse-hair-isolute-sle?hsLang=en) This application note describes the extraction of a panel of 18 steroid hormones from horse hair using ISOLUTE® SLE+ plates prior to LC/MS-MS analysis. The simple sample preparation procedure delivers clean extracts and analyte recoveries greater than 80% with RSDs lower than 5% for most analytes. Linearity of greater than 0.999 is achieved for all analytes in the range 0.5-500 pg/mg of hair. More documents × ## Your Cart Request a Quote Checkout Recommended products Supported Liquid Extraction plates and columns designed to provide high analyte recoveries, and clean, protein and phospholipid free extracts. Methods are easy to develop, and automation is simple. [ ISOLUTE® SLE+](https://www.biotage.com/products/isolute-sle-supported-liquid-extraction-cartridges-plates) Eliminate conditioning and equilibration with EVOLUTE® EXPRESS load-wash-elute SPE. Robust, reliable SPE, giving ultra-pure extracts and high recoveries. Specifically developed for quantification by LC-MS/MS. [ EVOLUTE® EXPRESS](https://www.biotage.com/polymeric-solid-phase-extraction) Extremely efficient removal of matrix components and hydrolysis enzyme from urine and other biological fluid samples, using a simple pass through workflow. [ ISOLUTE® HYDRO DME+](https://www.biotage.com/products/isolute-hydro-dme-dual-mode-extraction-cartridges-plates) Bead mill homogenization for challenging matrices prior to any sample preparation and extraction.  [ Biotage® Lysera](https://www.biotage.com/products/lysera-bead-mill-homogenizer) Powerful, user friendly automation systems for Supported Liquid Extraction (SLE), Solid Phase Extraction (SPE), Phospholipid Depletion (PLD) and Protein Precipitation (PPT) based methods, in plate or column formats. [ Biotage® Extrahera™](https://www.biotage.com/products/solid-phase-extraction-systems) Evaporation of up to 48 samples with independent control of flow in each row.  [ TurboVap® LV](https://www.biotage.com/products/turbovap-evaporator) ### About Biotage Biotage is a global supplier and solutions partner to a wide range of customers within drug discovery and development and analytical testing. With strong expertise in separation and purification technologies, and a focus on leveraging intelligent workflow solutions, we aim to efficiently support the advancement and protection of human health. [![Biotage-Logo-2012-white](https://f.hubspotusercontent20.net/hubfs/7813877/Biotage/Biotage-Logo-2012-white.png) ](https://www.biotage.com/) - [Legal Terms](https://www.biotage.com/legal-terms) Copyright © 2025 Biotage ** Ask a specialist ##### Ask a specialist Doping Control Sample Preparation