Avoiding cross talk in 96-well based sample preparation

This guide aims to describe simple practical strategies, hints and tips designed to mitigate or avoid cross-well contamination or ‘cross talk’ in high throughput 96-well based sample preparation techniques. All aspects of the sample preparation procedure should be considered when trying to avoid or eliminate the potential for cross talk. Sample preparation hardware (e.g. extraction and collection plates), processing equipment and conditions (including evaporation) and method parameters (e.g. solvents and volumes) are important aspects to optimize.

Literature number: PPS387