ISOLUTE® C18
Solid-phase extraction cartridges and plates
A retentive, non-polar sorbent for extraction of a range of analytes from aqueous samples using a non-polar retention mechanism.
ISOLUTE® C18 is the most commonly used C18 sorbent for the extraction of acidic, neutral and basic compounds from aqueous sample matrices. The sorbent is not end-capped, and secondary silanol interactions can be exploited to enhance extract purity and method robustness for basic analytes.
ISOLUTE® C18 is available in a wide range of SPE cartridges, 96-well plate formats and as loose sorbent (100 g pack). As an alternative, end capped C18, with reduced secondary interaction is also available.
Specifications
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Chemical description
Octadecyl (end capped) functionalized silica. Manufactured using trifunctional silane.
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Sorbent type
Non-polar
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Average particle size
50 µm
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Pore diameter
60 Å
Resources
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Download
Product note
QuickStart guide to SPE
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Download
Technical note
Method development guidelines: solid phase extraction using non-polar, silica based ISOLUTE® SPE sorbents for the extraction of aqueous samples
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Download
Product note
General approach to the extraction of basic drugs from biological fluids using non-polar ISOLUTE® SPE cartridges
Ordering information
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