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Oligonucleotide synthesis service

Synthesis of difficult and complex oligonucleotides at high purity

Synthesis and delivery of  DNA/RNA oligonucleotides, aptamers and triphosphates tailored to your needs.
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We are experts in the synthesis of difficult and complex oligonucleotides at high purity. We produce oligonucleotides for companies around the globe, using patented techniques and always with an emphasis on quality and reliability.
 
For companies looking to have specific oligonucleotides produced for on-going projects, or who need additional outsourced expertise for a difficult sequence or sequences, Biotage can supply single and multiple oligonucleotides synthesised to your specification.
 

We are also able to partner with organisations to develop cutting-edge sequences for advanced research needs, and are a reliable partner for leading biotherapeutic and diagnostic companies.

 
All of our synthesis services come with rigorous discussion and consulting, to ensure that our experts deliver exactly what is required. Our laboratories were founded by acknowledged leaders in oligonucleotide synthesis, so working with us ensures the best knowledge is at our customers' disposal.
 

Quality

Quality is built into our procedures ana methodologies. Our scientists, at the forefront of oligonucleotide synthesis, are able to produce molecules to the highest level of quality, each time and every time.

Reliability

With quality built into our procedures, our customers can rely on Biotage with every single order. We strive to produce the highest quality of product, every time.

Delivery

In many projects requiring oligonucleotides, time is of the essence. The timely delivery of products to our customer's agreed timelines means that they can be sure their project runs on time and delivers the result they need, when they need them.

Capabilities

  • Synthesis scale

    From 0.2 µmol to 1 mmol and above

  • Modifications

    Unlimited, from dyes and quenchers to modified bases and backbones

  • Purification

    HPLC or PAGE

  • Analysis

    UPLC/MS or CE

  • Final product format

    Lyophilised or adjusted to a specific concentration

  • Length

    Up to 200 bases, including complex modifications

Resources

  • Brochure

    Custom oligonucleotide synthesis
    Download

  • White paper

    Solid phase oligonucleotide synthesis
    Download

  • Customer case

    Partnership for advanced therapies with Eleven Therapeutics
    Read article

  • White paper

    Oligonucleotide drug molecules
    Download

  • Application note

    Synthesis of long oligonucleotides
    Read article

  • Application note

    Quality control data for oligonucleotides of varying lengths 
    Read article