Biotage® PhyPrep
Automated plasmid purification
Focus on delivery. Not prep time.
Manual prep is slow and resource-heavy, especially at scale. Biotage® PhyPrep automates plasmid purification, delivering high-purity, low endotoxin DNA from cell pellets at Maxi, Mega, and Giga scales.
Cut prep time by up to 40% and focus on what matters —driving innovation.
Reproducibility you can trust
Biotage® PhyPrep delivers 80–90% supercoiled plasmids with high yield, exceptional purity, and low endotoxin levels, across Maxi, Mega and Giga scales. Whether you’re prepping for transfection, gene therapy, or vaccine development, Biotage® PhyPrep’s proprietary dual-flow chromatography, ensures consistent results. Batch after batch.
Built to scale with your science
From Maxi to Giga, Biotage® PhyPrep delivers up to 10 mg of high-purity, low endotoxin plasmid DNA per run, automated and hands-free. Whether handling a few samples or scaling up for production, Biotage® PhyPrep adapts to your workflow with consistent, reliable performance.
Smart, intuitive software
Biotage® PhyPrep makes plasmid purification effortless with a user-friendly touchscreen interface and minimal setup. Pre-aliquoted buffers and intuitive protocols ensure seamless integration into your lab.
Specifications
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Plasmid yield
Up to 1/5/10 mg from 2/4.5/7 g cell wet weight using rich media and a high-copy plasmid at Maxi/Mega/Giga scale, respectively.
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Plasmid DNA
Transfection-grade (with rich media and high copy plasmids);< 80-90% supercoiled plasmid DNA
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Throughput
1-4 samples per run
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Processing time
~42 min (maxi, 1-2 samples), ~298 min (giga, 1-2 samples)
Resources
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Brochure
Biotage® PhyPrep
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Product note
Automated plasmid purification at Maxi, Mega and Giga scales
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Download
Poster
Presented by KTH - Streamlined process for automated plasmid purification
reduces labour time and increases titres for AAV production -
Read article
Application note
The Biotage® PhyPrep maxi mega giga instrument and fully automated plasmid purification for transient transfection and mammalian protein production
Ordering information
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