Optimize your PFAS sample preparation workflow

The detection of per- and polyfluoroalkyl substances (PFAS) within our air, water, and soil has confirmed their place as persistent pollutants that pose significant health risks upon human exposure, including metabolic changes, elevated cholesterol levels, and increased cancer risks.

As governments are spurred to take action and monitor the levels of these compounds, Biotage understands the need for simple and robust sample preparation procedures and has a number of solutions tailored to environmental and biological fluid matrices.

Homogenization

The concentration of PFAS analytes can be higher in certain portions of solid samples, therefore sample homogenization is key in screening solid matrices for toxic substances.

The Biotage® Lysera bead mill homogenizer is specifically designed for automating the grinding, lysing, and homogenizing of biological samples.

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Processing

Streamlined sample preparation with advanced automation that minimizes manual handling and reduces the risk of contamination is key for PFAS extractions.

Biotage® PrepXpert-8 boosts throughput, ensures traceability, and simplifies complex PFAS extractions from water and environmental samples.

Biotage® Extrahera™ Classic workstation processes both cartridges and plates, and coupled with its GLP capabilities, is the perfect fit for sample preparation of biological samples. Biotage® Extrahera™ LV-200 has the same GLP capabilities and is designed for plate processing.

Matrix

Method

EVOLUTE® PFAS | WAX SPE cartridge for PFAS extraction

High-purity media and components optimized for PFAS extraction from environmental matrices.

EVOLUTE® PFAS+ | Solid-phase extraction cartridge for PFAS analysis

High-purity SPE cartridges for precise PFAS extraction with low background and high recovery across a broad PFAS analyte range.

ISOLUTE® PLD+ for PFAS | Protein and phospholipid removal products

Fast, effective clean-up for PFAS analytes in biological fluids.

ISOLUTE® 101 | Solid-phase extraction cartridge

An unmodified polystyrene-divinylbenzene copolymer, for extraction of a range of polar analytes from aqueous samples.

EVOLUTE® EXPRESS WAX | Solid-phase extraction cartridges and plates

Polymeric mixed-mode cartridges and plates for for extraction of strongly acidic analytes from aqueous samples.

Biotage® Mikro SPE | Solid-phase extraction microelution plate

Excellent sample clean-up, delivering reproducible and high-sensitivity analytical results.

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Evaporation

PFAS testing laboratories require evaporation systems which are clean, reliable, and affordable to evaporate the extracts resulting from the sample processing.

The TurboVap® LV system can evaporate extracts in methanol to dryness consistent with typical PFAS procedures.

Designed to evolve with your sample throughput, the TurboVap® 96 Dual comes ready to support 96 well plates.

Synthesis

Purification

Evaporation

Sample extraction and clean-up

Bioanalysis and clinical testing

Forensic toxicology and doping control

Environmental testing

Food safety

Biomolecule purification

Peptides

Small molecules

Optimize your PFAS sample preparation workflow

Homogenization

Processing

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Evaporation

Literature, blogs and webinars