Automate your bioanalysis sample preparation workflow
Discover Biotage’s smart sample preparation solutions and find lots of useful resources for bioanalysis applications.
Pre-treatment
The system is specifically designed for the grinding, lysing and homogenization of samples prior to any form of sample extraction. Using sample tubes pre-filled with a variety of beads, Biotage® Lysera vigorously and uniformly shakes the tubes providing an efficient, consistent, high-yield and quality homogenization usually in less than 40 seconds. Samples are enclosed in individual vessels to prevent cross contamination and can accommodate dry or wet homogenization of samples from milligram to gram quantities.
Extraction
The Biotage® Extrahera™ family of automated sample preparation workstations allows rapid and efficient plate (and/or cartridge) extractions to a high level of accuracy and precision.
The Biotage® Extrahera™ LV-200 is dedicated to 96-well arrays for microelution technologies and classical 96-well SPE, SLE, and PPT or PLD consumable formats.
The Biotage® Extrahera™ Classic is a powerful system for SPE, SLE, PLD and PPT based methods, in both plate and cartrisge formats.
Evaporation
Resources
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Read blog
What are the 5 steps of SPE?
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What sorbent should I use? Selecting the correct SPE chemistry
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How do neutral analytes and SPE EVOLUTE® EXPRESS ABN work?
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How do weakly acidic analytes and EVOLUTE® EXPRESS AX work?
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How do weakly basic analytes and SPE EVOLUTE® EXPRESS CX work?
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How do strongly basic analytes and SPE EVOLUTE® EXPRESS WCX work?
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Zolmitriptan, plasma
Automated extraction of Zolmitriptan from plasma using ISOLUTE® SLE+ with Biotage® Extrahera™ Classic prior to UHPLC-MS/MS analysis -
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Oxytocin and vasopressin, serum
Extraction of oxytocin and vasopressin from serum using EVOLUTE® EXPRESS ABN prior to LC-MS/MS analysis -
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Peptide hormones, plasma
Simultaneous extraction of aldosterone and angiotensin I and II from human plasma using EVOLUTE® EXPRESS ABN prior to LC/MS analysis -
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Vitamin D metabolites, serum
Extraction of Vitamin D metabolites from human serum using ISOLUTE® SLE+ in 96-fixed well plate format prior to LC-MS/MS analysis -
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Desmopressin, serum
Extraction of desmopressin from serum using EVOLUTE® EXPRESS WCX prior to LC-MS/MS analysis
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Watch webinar
Reducing bioanalysis bottlenecks
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Optimizing sample prep for bioanalysis
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Watch webinar
Method development strategies
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Watch webinar
The might of Mikro
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Read blog
Protein precipitation vs. traditional protein crash: what's best?
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How to choose between SPE and SLE?
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Techniques for disrupting protein binding in sample preparation
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How do I come up with a starting point for my SPE method?
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When should I choose a mixed-mode SPE?
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What is the role of LogP in sample prep methods?
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How to automate sample prep in the GLP analytical lab
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The revolution of microelution in solid phase extraction
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When should I choose SLE or SPE for sample cleanup?
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Read blog
Vacuum or positive pressure for processing samples: what's best?
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Read article
Fuji Pharma, Japan
Improving sustainability and throughput by automating sample preparation with the Biotage® Extrahera™ LV-200
Recommended products
ISOLUTE® SLE+ | Supported liquid extraction plates and cartridges
Load-wait-elute procedure for stress free extraction of analytes from biological fluids, providing high analyte recoveries and clean extracts.
Biotage® Mikro SPE | Solid-phase extraction microelution plate
Excellent sample clean-up, delivering reproducible and high-sensitivity analytical results.
EVOLUTE® EXPRESS ABN | Solid-phase extraction cartridges and plates
EVOLUTE® EXPRESS ABN is a modified PS-DVB polymeric sorbent designed to extract acidic, basic, and neutral analytes with consistent, dependable performance.
ISOLUTE® PLD+ | Protein and phospholipid removal plates and cartridges
Effortlessly enhance analyte sensitivity with effective but extremely simple sample clean-up for LC-MS/MS analysis.
Biotage® Lysera | Bead mill homogenizer
Designed for automating the grinding, lysing, and homogenizing of biological, food and environmental samples prior to sample preparation.
Biotage® Extrahera™ LV-200 | Automated sample preparation workstation
The Biotage® Extrahera™ LV-200 workstation automates low-volume sample prep with precision, GLP compliance, and intuitive software in a compact footprint.
Biotage® Extrahera™ Classic | Multi-format sample prep workstation
An automated workstation for sample prep processing in plates and cartridges and parallel peptide purification.
TurboVap® 96 Dual | Plate evaporator with intelligent heating
Dual-plate evaporation with intelligent heating and flow control for high-throughput workflows.