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ISOLUTE® HCX-Q

Solid-phase extraction cartridges and plates

A mixed-mode sorbent providing clean extracts for strongly basic compounds from complex biological fluid samples using a dual retention mechanism.
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biotage-isolute-hcx-q-cartridge

ISOLUTE® HCX-Q combines non-polar and weak cation exchange retention mechanisms to isolate strongly basic analytes from complex aqueous matrices such as urine and plasma. Analutes are initially retained by the non-polar retention mechanism, which is unaffected by high or variable ionic strength of the sample matrix. The pH control and salt removal at the sample application stage ensures that the polybasic drug or quaternary amine is retained by a robust cation exchange retention mechanism.

Specifications

  • Chemical description

    Octyl (C8, non-endcapped) and carboxylic acid (COO-)

  • Sorbent type

    Mixed-mode (non-polar and weak cation exchange)

  • Average particle size

    50 µm

  • Pore diameter

    60 Å

Resources

  • Product note

    QuickStart guide to SPE

    Download

  • Technical note

    Generic method for the extraction of quaternary amines and polybasic drugs from biological fluids using ISOLUTE® HCX-Q mixed-mode SPE cartridges and 96-well plates

    Download

Ordering information

Part no.
Name
Pack size
Price
Part no.
986-0005-A
Name
ISOLUTE® HCX-Q 50 mg/1 mL
Pack size
100
Price
302 USD
Add to cart
Part no.
986-0100-P01
Name
ISOLUTE®-96 HCX-Q 100 mg Fixed Well Plate
Pack size
1
Price
438 USD
Add to cart
Part no.
986-0025-P01
Name
ISOLUTE®-96 HCX-Q 25 mg Fixed Well Plate
Pack size
1
Price
407 USD
Add to cart

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