ISOLUTE® SCX-2
Metal scavenger/scavenger
As a bound sulfonic acid, ISOLUTE® SCX-2 has a natural propensity to bind alkali and some transition metal group metals, which means that it can be used as a scavenger for metals with a +I or +II oxidation state. ISOLUTE® SCX-2 is typically used as a metal scavenger when the target product is not basic, to avoid the obvious acid/base product binding interactions with the scavenger.
It can also be used to scavenge basic impurities and thereby purify reaction mixtures. Passing a reaction mixture through ISOLUTE® SCX-2 will result in removal of
all basic components in the mixture.
With lot control, QA/QC documentation, SDS, ISO 9001/14001 registration, BSE/TSE statement and shelf-life statement, ISOLUTE® SCX-2 also supports the audit trail.
Specifications
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Chemical name
Silica Propylsulfonic Acid (Si-propylsulfonic acid; SCX-2)
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Resin type
Bioanalytical grade silica
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Application
Scavenger of amine, Catch-and-Release, Acid catalyst
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Typical scavenging conditions
Stir crude reaction mixture with 2–4 equivalents for 1 h and filter
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Compatible solvents
Methanol (MeOH), Dichloromethane (DCM), Acetonitrile (MeCN), Acetone, Ethyl Acetate (EtOAc), N,N-Dimethylformamide (DMF), Dimethylsulfoxide (DMSO)
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Storage
Cool, dry location
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Shelf-life / retest date
5 years / typically annually thereafter depending on process
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Capacity
0.7 mmol/g
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Particle size
40-60 microns
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Bulk density
700g /L
Resources
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Download
Product note
ISOLUTE® SCX-2 metal scavenger
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Download
Poster
Metal scavengers in process chemistry: An investigative study
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Download
Poster
New applications of ruthenium scavenging
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Read article
Application note
Metal scavengers: Metal mitigation, extractables and regulatory perspectives
Ordering information
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