EPA Method 1668A: Chlorinated Biphenyl Congeners by HRGC/HRMS

Method 1668A is used for determining the level of chlorinated biphenyl congeners by high resolution gas chromatography with high resolution mass spectrometry (HRGC/HRMS). For aqueous samples (samples containing less than 1% solids) - Stable isotopically labelled analogs of the toxic PCB's are spiked into a 1L sample, and the sample is extracted using the Biotage® Horizon 4790 Automated Extraction System along with the Atlantic™ C18 solid phase extraction (SPE) disk. Samples are then dried and concentrated using the DryVap® Automated Drying and Concentrating System with DryDisk® technology. This application note describes implementation of this method using Biotage® Horizon 5000; 4790 and VacMaster Disk systems.