Custom oligonucleotide synthesis by ATDBio
From standard DNA and RNA sequences to complex modified oligos
ATDBio is based in Southampton, UK, and became part of Biotage in 2021, combining ATDBio’s expertise in nucleic acid chemistry with Biotage’s global presence in life sciences.
We work with companies around the globe to supply oligonucleotides for research, diagnostic and therapeutic development projects.
From routine sequences to more complex modified oligos, our team provides practical technical support with a strong focus on quality, flexibility and reliability. Customers can discuss their required sequence, modifications, purity requirements and intended application directly with experienced oligonucleotide chemists.
Using our understanding of oligonucleotide chemistry, we identify suitable approaches for production, purification and analysis, helping deliver high-quality oligonucleotides in line with the agreed specification.
Quality
Quality is built into our procedures ana methodologies. Our scientists, at the forefront of oligonucleotide synthesis, are able to produce molecules to the highest level of quality, each time and every time.
Reliability
With quality built into our procedures, our customers can rely on Biotage with every single order. We strive to produce the highest quality of product, every time.
Delivery
In many projects requiring oligonucleotides, time is of the essence. The timely delivery of products to our customer's agreed timelines means that they can be sure their project runs on time and delivers the result they need, when they need them.
Capabilities
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Synthesis scale
From 0.2 µmol to 1 mmol and above -
Modifications
Unlimited, from dyes and quenchers to modified bases and backbones -
Purification
HPLC or PAGE -
Analysis
UPLC/MS or CE -
Final product format
Lyophilised or adjusted to a specific concentration -
Length
Up to 200 bases, including complex modifications
Resources
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Download
Brochure
Custom oligonucleotide synthesis -
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White paper
Solid phase oligonucleotide synthesis -
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Customer case
Partnership for advanced therapies with Eleven Therapeutics -
Download
White paper
Oligonucleotide drug molecules -
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Application note
Synthesis of long oligonucleotides -
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Application note
Quality control data for oligonucleotides of varying lengths