AAV PhyTip® column
Protein purification column
Automated purification of adeno-associated viruses using CaptureSelect™ AAVX and AAV9 resins for high selectivity, 60-80% recovery, and fast, consistent results.
Adeno-associated virus (AAV) is a non-enveloped virus commonly engineered to deliver DNA to target cells. Its single-stranded DNA genome (~4.7 kb) makes it a preferred vector for gene therapy, enabling delivery to diverse cell types including muscle, vascular endothelial, and neuronal cells.
In downstream processing, affinity chromatography effectively removes impurities such as plasmid DNA and host cell RNA/DNA, followed by anion exchange polishing to eliminate empty capsids.
PhyTip® columns with CaptureSelect™ AAVX affinity matrix are designed for high selectivity and capacity in the purification of both naturally occurring and synthetic AAV serotypes. The CaptureSelect™ AAVX resin binds efficiently to AAV1–AAV9, AAVrh10, and a range of synthetic variants used in gene therapy applications.
Using dual flow chromatography, PhyTip® columns pump samples back and forth across the packed resin bed to maximize binding. Packed with a high-capacity AAV affinity resin, they routinely deliver purified protein samples with 60–80% recovery.
AAV PhyTip® columns are compatible with most 8-, 12- and 96-channel automated liquid handling systems, providing fast and consistent purification across multiple formats.
CaptureSelect™ is a trademark of Thermo Fisher Scientific.
Resources
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Download
Brochure
Biomolecule purification with PhyTip® columns
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Product note
POROS CaptureSelect™ AAVX PhyTip® columns
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Read article
White paper
Accelerating high throughput with PhyTip® columns
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White paper
PhyTip® columns versus other common technologies: A comparative analysis of protein purification yields
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Read article
White paper
PhyTip® columns versus other common technologies: a comparative analysis of protein purification efficiency and yield consistency
Ordering information
Part no.
Name
Pack size
Price
Part no.
PTH-91-10-62
Name
PhyTip® 1 mL vol, 10 µL AVIPure AAV9, Hamilton (96/pk)
Pack size
96
Price
982 USD
Part no.
PTR-91-10-62
Name
PhyTip® 1 mL vol, 10 µL AVIPure AAV9, Rainin (96/pk)
Pack size
96
Price
1151 USD
Part no.
PTT-91-10-62
Name
PhyTip® 1 mL vol, 10 µL AVIPure AAV9, Tecan (96/pk)
Pack size
96
Price
1102 USD
Part no.
PTH-91-10-61
Name
PhyTip® 1 mL vol, 10 µL POROS CS AAV9, Hamilton (96/pk)
Pack size
96
Price
773 USD
Part no.
PTR-91-10-61
Name
PhyTip® 1 mL vol, 10 µL POROS CS AAV9, Rainin (96/pk)
Pack size
96
Price
773 USD
Part no.
PTT-91-10-61
Name
PhyTip® 1 mL vol, 10 µL POROS CS AAV9, Tecan (96/pk)
Pack size
96
Price
773 USD
Part no.
PTH-91-16-61
Name
PhyTip® 1 mL vol, 160 µL POROS CS AAV9, Hamilton (96/pk)
Pack size
96
Price
3032 USD
Part no.
PTR-91-20-62
Name
PhyTip® 1 mL vol, 20 µL AVIPure AAV9, Rainin (96/pk)
Pack size
96
Price
1517 USD
Part no.
PTT-91-20-62
Name
PhyTip® 1 mL vol, 20 µL AVIPure AAV9, Tecan (96/pk)
Pack size
96
Price
1656 USD
Part no.
PTH-91-20-61
Name
PhyTip® 1 mL vol, 20 µL POROS CS AAV9, Hamilton (96/pk)
Pack size
96
Price
900 USD
Part no.
PTR-91-20-61
Name
PhyTip® 1 mL vol, 20 µL POROS CS AAV9, Rainin (96/pk)
Pack size
96
Price
900 USD
Part no.
PTT-91-20-61
Name
PhyTip® 1 mL vol, 20 µL POROS CS AAV9, Tecan (96/pk)
Pack size
96
Price
900 USD
Part no.
PTH-91-40-62
Name
PhyTip® 1 mL vol, 40 µL AVIPure AAV9, Hamilton (96/pk)
Pack size
96
Price
2629 USD
Part no.
PTR-91-40-62
Name
PhyTip® 1 mL vol, 40 µL AVIPure AAV9, Rainin (96/pk)
Pack size
96
Price
2611 USD
Part no.
PTT-91-40-62
Name
PhyTip® 1 mL vol, 40 µL AVIPure AAV9, Tecan (96/pk)
Pack size
96
Price
2762 USD
Part no.
PTH-91-40-61
Name
PhyTip® 1 mL vol, 40 µL POROS CS AAV9, Hamilton (96/pk)
Pack size
96
Price
2032 USD
Part no.
PTR-91-40-61
Name
PhyTip® 1 mL vol, 40 µL POROS CS AAV9, Rainin (96/pk)
Pack size
96
Price
2032 USD
Part no.
PTT-91-40-61
Name
PhyTip® 1 mL vol, 40 µL POROS CS AAV9, Tecan (96/pk)
Pack size
96
Price
2032 USD
Part no.
PTH-91-80-62
Name
PhyTip® 1 mL vol, 80 µL AVIPure AAV9, Hamilton (96/pk)
Pack size
96
Price
4843 USD
Part no.
PTT-91-80-62
Name
PhyTip® 1 mL vol, 80 µL AVIPure AAV9, Tecan (96/pk)
Pack size
96
Price
4976 USD
Part no.
PTH-91-80-61
Name
PhyTip® 1 mL vol, 80 µL POROS CS AAV9, Hamilton (96/pk)
Pack size
96
Price
2032 USD
Part no.
PTR-91-80-61
Name
PhyTip® 1 mL vol, 80 µL POROS CS AAV9, Rainin (96/pk)
Pack size
96
Price
2032 USD
Part no.
PTT-91-80-61
Name
PhyTip® 1 mL vol, 80 µL POROS CS AAV9, Tecan (96/pk)
Pack size
96
Price
2032 USD
Part no.
PTR-92-20-62
Name
PhyTip® 200 ul vol, 20 µL AVIPure AAV9, Rainin (96/pk)
Pack size
96
Price
1601 USD
Part no.
PTT-92-20-62
Name
PhyTip® 200 µL vol, 20 µL AVIPure AAV9, Tecan (96/pk)
Pack size
96
Price
1471 USD
Part no.
PTT-95-20-62
Name
PhyTip® 500 µL vol, 20 µL AVIPure AAV9, Tecan (96/pk)
Pack size
96
Price
1747 USD
Part no.
PTT-95-20-61
Name
PhyTip® 500 µL vol, 20 µL POROS CS AAV9, Tecan (96/pk)
Pack size
96
Price
957 USD
Part no.
PTT-95-40-62
Name
PhyTip® 500 µL vol, 40 µL AVIPure AAV9, Tecan (96/pk)
Pack size
96
Price
2854 USD
Part no.
PTT-95-40-61
Name
PhyTip® 500 µL vol, 40 µL POROS CS AAV9, Tecan (96/pk)
Pack size
96
Price
2032 USD
Part no.
PTT-95-80-62
Name
PhyTip® 500 µL vol, 80 µL AVIPure AAV9, Tecan (96/pk)
Pack size
96
Price
5061 USD
Part no.
PTT-95-80-61
Name
PhyTip® 500 µL vol, 80 µL POROS CS AAV9, Tecan (96/pk)
Pack size
96
Price
2032 USD
Part no.
PTB-91-10-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 10 µL resin per column, Beckman
Pack size
96
Price
1260 USD
Part no.
PTX-91-10-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 10 µL resin per column, DD/Biotix
Pack size
96
Price
1260 USD
Part no.
PTH-91-10-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 10 µL resin per column, Hamilton
Pack size
96
Price
1260 USD
Part no.
PTR-91-10-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 10 µL resin per column, MEA 2
Pack size
96
Price
1260 USD
Part no.
PTT-91-10-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 10 µL resin per column, Tecan
Pack size
96
Price
1260 USD
Part no.
PTB-91-16-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 160 µL resin per column, Beckman
Pack size
96
Price
Get a quote
Part no.
PTX-91-16-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 160 µL resin per column, DD/Biotix
Pack size
96
Price
Get a quote
Part no.
PTH-91-16-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 160 µL resin per column, Hamilton
Pack size
96
Price
Get a quote
Part no.
PTR-91-16-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 160 µL resin per column, MEA 2
Pack size
96
Price
Get a quote
Part no.
PTT-91-16-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 160 µL resin per column, Tecan
Pack size
96
Price
Get a quote
Part no.
PTB-91-20-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 20 µL resin per column, Beckman
Pack size
96
Price
1773 USD
Part no.
PTX-91-20-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 20 µL resin per column, DD/Biotix
Pack size
96
Price
1773 USD
Part no.
PTH-91-20-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 20 µL resin per column, Hamilton
Pack size
96
Price
1773 USD
Part no.
PTR-91-20-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 20 µL resin per column, MEA 2
Pack size
96
Price
1773 USD
Part no.
PTT-91-20-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 20 µL resin per column, Tecan
Pack size
96
Price
1773 USD
Part no.
PTR-91-32-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 320 µL resin per column, MEA 2
Pack size
96
Price
Get a quote
Part no.
PTB-91-40-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 40 µL resin per column, Beckman
Pack size
96
Price
3539 USD
Part no.
PTX-91-40-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 40 µL resin per column, DD/Biotix
Pack size
96
Price
3539 USD
Part no.
PTH-91-40-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 40 µL resin per column, Hamilton
Pack size
96
Price
3539 USD
Part no.
PTR-91-40-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 40 µL resin per column, MEA 2
Pack size
96
Price
3539 USD
Part no.
PTT-91-40-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 40 µL resin per column, Tecan
Pack size
96
Price
3539 USD
Part no.
PTB-91-80-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 80 µL resin per column, Beckman
Pack size
96
Price
6319 USD
Part no.
PTX-91-80-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 80 µL resin per column, DD/Biotix
Pack size
96
Price
6319 USD
Part no.
PTH-91-80-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 80 µL resin per column, Hamilton
Pack size
96
Price
6319 USD
Part no.
PTR-91-80-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 80 µL resin per column, MEA 2
Pack size
96
Price
6319 USD
Part no.
PTT-91-80-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (1 mL volume) containing 80 µL resin per column, Tecan
Pack size
96
Price
6319 USD
Part no.
PTV-92-20-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (200 µL volume) containing 20 µL resin per column, Agilent Bravo
Pack size
96
Price
1773 USD
Part no.
PTB-92-20-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (200 µL volume) containing 20 µL resin per column, Beckman
Pack size
96
Price
1773 USD
Part no.
PTR-92-20-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (200 µL volume) containing 20 µL resin per column, MEA 2
Pack size
96
Price
1773 USD
Part no.
PTT-92-20-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (200 µL volume) containing 20 µL resin per column, Tecan
Pack size
96
Price
1773 USD
Part no.
PTB-92-05-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (200 µL volume) containing 5 µL resin per column, Beckman
Pack size
96
Price
850 USD
Part no.
PTR-92-05-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (200 µL volume) containing 5 µL resin per column, MEA 2
Pack size
96
Price
850 USD
Part no.
PTT-92-05-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (200 µL volume) containing 5 µL resin per column, Tecan
Pack size
96
Price
850 USD
Part no.
PTX-93-20-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (300 µL volume) containing 20 µL resin per column, DD/Biotix
Pack size
96
Price
1773 USD
Part no.
PTH-93-20-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (300 µL volume) containing 20 µL resin per column, Hamilton
Pack size
96
Price
1773 USD
Part no.
PTX-93-05-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (300 µL volume) containing 5 µL resin per column, DD/Biotix
Pack size
96
Price
850 USD
Part no.
PTH-93-05-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (300 µL volume) containing 5 µL resin per column, Hamilton
Pack size
96
Price
850 USD
Part no.
PTT-95-16-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (500 µL volume) containing 160 µL resin per column, Tecan
Pack size
96
Price
Get a quote
Part no.
PTT-95-20-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (500 µL volume) containing 20 µL resin per column, Tecan
Pack size
96
Price
1773 USD
Part no.
PTT-95-40-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (500 µL volume) containing 40 µL resin per column, Tecan
Pack size
96
Price
3539 USD
Part no.
PTT-95-80-33
Name
POROS CaptureSelect™ AAVX PhyTip® columns (500 µL volume) containing 80 µL resin per column, Tecan
Pack size
96
Price
6319 USD
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