Biotage^® MP-Carbonate

Powerful Acid Scavenger, and Neutralise TFA or HCl Salts

Biotage® MP-Carbonate is a powerful supported base for reaction quenching, neutralizing amine hydrochlorides or trifluoroacetic acid salts and scavenging of a variety of acidic molecules such as carboxylic acids or acidic phenols.

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Biotage® MP-Carbonate Product Note

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Part numbers

Part No.	Description	Pack Size	List Price
800314	Biotage® MP-Carbonate, 1 kg	1		Add to quote/cart
800267	Biotage® MP-Carbonate, 10 g	1	95 USD	Add to quote/cart
800269	Biotage® MP-Carbonate, 100 g	1	573 USD	Add to quote/cart
800268	Biotage® MP-Carbonate, 25 g	1	194 USD	Add to quote/cart
800493	Biotage® MP-Carbonate, 3 g	1	46 USD	Add to quote/cart

Specifications

RESIN TYPE Macroporous poly(styrene-codivinylbenzene)

CHEMICAL NAME Macroporous triethylammonium methylpolystyrene carbonate (0.5% inorganic antistatic agent)

APPLICATION General base in promoting reactions. Ammonium salt neutralization (TFA/ HCL salts). Scavenger of organic acids such as carboxylic acids, boronic acids, HOBt, imidazoles, phenols, N-hydroxysuccinimide.

COMPATIBLE SOLVENTS DCM (3.0 mL/g), DCE (3.0 mL/g), THF (2.8 mL/g), DMF (2.9 mL/g) and aqueous mixtures thereof, no major incompatibilities (acids excepted)

BULK DENISTY 500g /L

TYPICAL SCAVENGING CONDITIONS 3 equivalents relative to substrate, 0.5–2 h, 20 ˚C

STORAGE Cool dry / closed container

SHELF-LIFE / RETEST DATE 5 years / typically annually thereafter depending on process

NOMINAL CAPACITY 2.8 mmol/g

PARTICLE SIZE 350-1250 microns

Biotage® MP-Carbonate Product Note

Benefits

For over 15 years Biotage has been guiding and leading the industry in supported reagents and scavengers.

Biotage® MP-Carbonate Product Note

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Efficiently deliver chemistry

More effective than traditional methods, polymer supported chemistry has been used widely in applications for over fifty years. Biotage supported reagents and scavengers are based on functionalized polystyrene or silica polymers and are 100% insoluble, therefore can be added to reactions and completely removed afterwards.

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Industry Proven

Key supplier to industry for over 15 years, used in numerous patents and cGMP process campaigns

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Robust, reliable, scalable and avoiding the need for problematic work-ups

From grams in research through to multi kilogram quantities in production campaigns. Biotage® MP-Carbonate may be used as a general base to quench reactions, neutralize amine hydrochlorides, or to scavenge a variety of acidic molecules such as carboxylic acids or acidic phenols.

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Fully Documented and Quality Assured

Inert, specifically-reactive and deployed to achieve a specific purpose. With lot control, QA / QC documentation, SDS, ISO 9001 / 14001 registration, BSE / TSE statement, shelf-life statement, these resins also support the audit trail.

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Biotage^® MP-Carbonate

Powerful Acid Scavenger, and Neutralise TFA or HCl Salts

Part numbers

Literature

Specifications