ISOLUTE® Si-TMT
Metal scavenger
Silica-based metal scavenger for the complete removal of palladium from pharma APIs and intermediates.
ISOLUTE® Si-TMT is an inert, robust, non-swelling adsorbent, which makes it ideal for restricted volume environments and fixed bed applications. It's used to efficiently scavenge residual palladium from catalysed reactions.
ISOLUTE® Si-TMT is easy to weigh and handle, does not stick to glassware when dried and does not require extensive washing for high product recovery.
With lot control, QA/QC documentation, SDS, ISO 9001/14001 registration, BSE/TSE statement and shelf-life statement, ISOLUTE® Si-TMT also supports the audit trail.
Specifications
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Chemical name
2,4,6-trimercaptotriazine silica
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Resin type
Bioanalytical grade silica
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Application
Scavenging palladium from aqueous and non-aqueous solutions
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Typical scavenging conditions
3–5 equivalents Si-TMT relative to palladium content, 30 min up to 24 h, room temperature, fixed bed or batch format
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Compatible solvents
Water, acetonitrile (MeCN), methanol, simethylsulfoxide (DMSO), sichloromethane (DCM), tetrahydrofuran (THF), N,N-dimethylformamide (DMF), dioxane
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Storage
Cool, dry location
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Shelf-life / retest date
5 years / typically annually thereafter depending on process
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Capacity
0.3 mmol/g
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Particle size
40-60 microns
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Bulk density
700g /L
Resources
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Download
Product note
ISOLUTE® Si-TMT metal scavenger
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Download
Poster
New applications of ruthenium scavenging
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Download
Poster
Metal scavengers in process chemistry: An investigative study
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Read article
Application note
Metal scavengers: metal mitigation, extractables and regulatory perspectives
Ordering information
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