ISOLUTE® Si-Trisamine
Metal scavenger
Scavenger of electrophiles from aqueous or organic solutions, as well as transition metals.
ISOLUTE® Si-Trisamine is a silica-bound equivalent of a trisamine base and can scavenge a variety of electrophiles, including aldehydes, acid chlorides, sulfonyl chlorides, isocyanates, isothiocyanates and heavy metal ions.
It acts as a powerful scavenger of transition metals, and can also be used as a work-up tool to remove electrophiles or acids in either batch or flow-mode, following traditional reflux heated or microwave synthesized reactions.
With lot control, QA/QC documentation, SDS, ISO 9001/14001 registration, BSE/TSE statement and shelf-life statement, ISOLUTE® Si-Trisamine also supports the audit trail.
Specifications
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Chemical name
Propyl tris-(2-aminoethyl) amine silica
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Resin type
Bioanalytical grade silica
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Application
Metal scavenging, scavenging acid chlorides, sulfonyl chlorides, isocyanates, chloroformates, anhydrides and other electrophiles
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Typical scavenging conditions
Si-trisamine (3 equiv.) agitated with metal or electrophile at room temperature for 30 min, or used as a fixed bed
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Compatible solvents
Water, acetonitrile, methanol, DMSO, DCM, THF, DMF, Dioxane
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Storage
Cool, dry location
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Shelf-life / retest date
5 years / typically annually thereafter depending on process
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Capacity
1.6 mmol/g
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Particle size
40-60 microns
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Bulk density
700g /L
Resources
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Download
Product note
ISOLUTE® Si-Trisamine metal scavenger
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Download
Poster
New applications of ruthenium scavenging
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Download
Poster
Metal scavengers in process chemistry: An investigative study
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Read article
Application note
Metal scavengers: metal mitigation, extractables and regulatory perspectives
Ordering information
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