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ISOLUTE® Si-Trisamine

Metal scavenger

Scavenger of electrophiles from aqueous or organic solutions, as well as transition metals.
biotage-si-trisamine-1kg

ISOLUTE® Si-Trisamine is a silica-bound equivalent of a trisamine base and can scavenge a variety of electrophiles, including aldehydes, acid chlorides, sulfonyl chlorides, isocyanates, isothiocyanates and heavy metal ions.

 

It acts as a powerful scavenger of transition metals, and can also be used as a work-up tool to remove electrophiles or acids in either batch or flow-mode, following traditional reflux heated or microwave synthesized reactions.

 

With lot control, QA/QC documentation, SDS, ISO 9001/14001 registration, BSE/TSE statement and shelf-life statement, ISOLUTE® Si-Trisamine also supports the audit trail.

Specifications

  • Chemical name

    Propyl tris-(2-aminoethyl) amine silica

  • Resin type

    Bioanalytical grade silica

  • Application

    Metal scavenging, scavenging acid chlorides, sulfonyl chlorides, isocyanates, chloroformates, anhydrides and other electrophiles

  • Typical scavenging conditions

    Si-trisamine (3 equiv.) agitated with metal or electrophile at room temperature for 30 min, or used as a fixed bed

  • Compatible solvents

    Water, acetonitrile, methanol, DMSO, DCM, THF, DMF, Dioxane

  • Storage

    Cool, dry location

  • Shelf-life / retest date

    5 years / typically annually thereafter depending on process

  • Capacity

    1.6 mmol/g

  • Particle size

    40-60 microns

  • Bulk density

    700g /L

Resources

  • Product note

    ISOLUTE® Si-Trisamine metal scavenger

    Download

  • Poster

    New applications of ruthenium scavenging

    Download

  • Poster

    Metal scavengers in process chemistry: An investigative study

    Download

  • Application note

    Metal scavengers: metal mitigation, extractables and regulatory perspectives

    Read article

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